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Septo-optic dysplasia and gastroschisis: trends in birth prevalence and association with maternal age

This study aims to describe the risk factors and trends in birth prevalence of septo-optic dysplasia (SOD) and gastroschisis between 1980 and 2023. This descriptive, population-based study of SOD and gastroschisis used Western Australian Register of Developmental Anomalies data from 1980 to 2023. Birth prevalence was calculated using Midwives Notification System data for all births after 20 weeks gestation.

Citation:
Cullingford DJ, Abraham MB, Siafarikas A, Blackmore AM, Downs J, Jacoby P, Baynam G, Choong CSY. Septo-optic dysplasia and gastroschisis: trends in birth prevalence and association with maternal age. Eur J Pediatr. 2025;184(5).

Keywords:
Birth prevalence; Congenital; Gastroschisis; Maternal age; Septo-optic dysplasia

Abstract:
This study aims to describe the risk factors and trends in birth prevalence of septo-optic dysplasia (SOD) and gastroschisis between 1980 and 2023. This descriptive, population-based study of SOD and gastroschisis used Western Australian Register of Developmental Anomalies data from 1980 to 2023. Birth prevalence was calculated using Midwives Notification System data for all births after 20 weeks gestation.