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Feasibility of home-based urine collection in children under 5 years in the ORIGINS birth cohort study: mixed method protocol and sample completion results

Urine is an attractive biospecimen for nutritional status and population health surveys. It is an excellent non-invasive alternative to blood for appropriate biomarkers in young children and is suitable for home-based collection, enabling representative collections across a population. However, the bulk of literature in this population is restricted to collection in primary care settings.

Citation:
Kidd CDA, Moumin NA, MacRae A, Green TJ, Silva DT, Prescott SL, D’Vaz N. Feasibility of home-based urine collection in children under 5 years in the ORIGINS birth cohort study: mixed method protocol and sample completion results. BMC Nutr. 2025;11(1).

Keywords:
Biobank; Child; Cohort; Completion rate; Home collection; Methods; ORIGINS; Participant feedback; Population; Urine

Abstract:
Urine is an attractive biospecimen for nutritional status and population health surveys. It is an excellent non-invasive alternative to blood for appropriate biomarkers in young children and is suitable for home-based collection, enabling representative collections across a population. However, the bulk of literature in this population is restricted to collection in primary care settings.