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Newly developed quantitative chest computed tomography (CT) outcomes designed specifically to assess structural abnormalities related to cystic fibrosis (CF) lung disease are now available. CFTR modulators potentially can reduce some structural lung abnormalities. We aimed to investigate the effect of CFTR modulators on structural lung disease progression using different quantitative CT analysis methods specific for people with CF (PwCF).
Children’s interstitial and diffuse lung disease (chILD) is a complex heterogeneous group of lung disorders. Gene panel approaches have a reported diagnostic yield of ~ 12%. No data currently exist using trio exome sequencing as the standard diagnostic modality.
Aspergillus Infections and Progression of Structural Lung Disease in Children with Cystic Fibrosis Rationale: Recent data show that Aspergillus
Of Pigs, Mice, and Men: Understanding Early Triggers of Cystic Fibrosis Lung Disease Of Pigs, Mice, and Men: Understanding Early Triggers of Cystic
CrossTalk opposing view: mucosal acidification does not drive early progressive lung disease in cystic fibrosis CrossTalk opposing view: mucosal
The cumulative effect of inflammation and infection on structural lung disease in early cystic fibrosis Lung inflammation and infection are common
Air trapping in early cystic fibrosis lung disease—Does CT tell the full story? Abstract Introduction: Mosaic attenuation on expiratory chest
Interleukin-1 is associated with inflammation and structural lung disease in young children with cystic fibrosis Early diagnosis and treatment in
Single-breath washout and association with structural lungdisease in children with cystic fibrosis Abstract Background: In children with cystic
The Kids Research Institute Australia lung health researchers have launched a campaign to raise awareness of wet cough and lung disease in Aboriginal children.