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Research

This prospective, longitudinal cohort study will examine airway sputum, lung function, and clinical surveillance data of children with bronchiectasis attending Perth Children’s Hospital.

Research

Respiratory oscillometry (or the forced oscillation technique) is a highly practical lung function test that can be applied in a wide range of clinical scenarios in children and adults, including the clinic, intensive care unit, patient home monitoring and emergency departments. Oscillometry measurements complement spirometry in detecting abnormal lung function, measuring effects of treatment such as inhaled corticosteroids or bronchodilators, and changes due to disease activity.

Research

This 14-color, 13-antibody optimized multicolor immunofluorescence panel (OMIP) was designed for deep profiling of neutrophil subsets in various types of human samples to contextualize neutrophil plasticity in a range of healthy and diseased states. Markers present in the OMIP allow the profiling of neutrophil subsets associated with ontogeny, migration, phagocytosis capacity, granule release, and immune modulation. 

Research

Neuromuscular disorders can lead to nocturnal hypoventilation. Accurate diagnosis of hypoventilation is imperative to guide treatment decisions. This study determined interobserver agreement for a number of definitions of nocturnal hypoventilation in children and adolescents with neuromuscular disorders.

Research

The Global Lung Function Initiative has worked to develop all‐age, multi‐ethnic reference equations for the major clinical lung function tests

Research

Slightly less than 1 h of general anaesthesia in early infancy does not alter neurodevelopmental outcome at age 5 years

Research

While spirometry contributes to asthma diagnosis and management in older children, it has a limited role in younger children whom are unable to perform FOM.

Research

Group Chairs and early career members highlight some of the most interesting findings in the field of paediatrics presented at the 2018 international ERS Congress

Research

We aimed to systematically review and assess the performance of all published models that predicted development of COPD

Research

Despite advances in asthma therapeutics, the burden remains highest in preschool children; therefore, it is critical to identify primary care tools that distinguish preschool children at high risk for burdensome disease for further evaluation.