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Rare childhood cancers have not benefited to the same extent from the gains that have been made for their frequently occurring counterparts.

The class 1A aldehyde dehydrogenase (ALDH1A) subfamily of genes encode enzymes that function at the apex of the retinoic acid (RA) signalling pathway.

Complement receptor 2 (CR2/CD21) plays an important role in the generation of normal B cell immune responses.

Medulloblastoma is the most common form of malignant paediatric brain tumour and is the leading cause of childhood cancer related mortality.

Our study provides evidence that OT-82 is a promising new therapeutic strategy for a broad spectrum of high-risk pediatric acute lymphoblastic leukemia

The largest GWAS meta-analysis conducted to date associating SNPs to venous thromboembolism in children and adolescents treated on childhood ALL protocols

The aim of our study was to investigate whether CBL0137 has potential as a therapeutic and chemopotentiating compound in MLL-r leukemia

Our approach to hematopoietic progenitor cells mobilization resulted in highly effective HPC harvest in children and adolescents with high-risk cancers

Children with Primary Central Nervous System Lymphoma and no immunodeficiency have a good outcome

Invasive fungal infections are more common in children with high-risk acute lymphoblastic leukaemia and in relapsed disease