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Cohort profile: Pregnancy and childhood epigenetics (PACE) consortiumCurrently, DNA methylation is the most studied epigenetic phenomenon in large populations
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Investment in child and adolescent health and development: key messages from Disease Control Priorities, 3rd EditionThe realisation of human potential for development requires age-specific investment throughout the 8000 days of childhood and adolescence.
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Activation of ERBB4 in Glioblastoma Can Contribute to Increased Tumorigenicity and Influence Therapeutic ResponseThe functional effects of increased ERBB4 activation identify ERBB4 as a potential prognostic and therapeutic target
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Improving delivery of secondary prophylaxis for rheumatic heart disease in a high-burden setting: Outcome of a stepped-wedge, community, randomized trialThis strategy did not improve adherence to rheumatic heart disease secondary prophylaxis within the study time frame.
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Qualitative Evaluation of a Complex Intervention to Improve Rheumatic Heart Disease Secondary ProphylaxisA multifaceted intervention was implemented using quality improvement and chronic care model approaches to improve delivery of penicillin prophylaxis for rheumatic heart disease
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The school experiences of children and adolescents with type 1 diabetes in Western AustraliaElevated levels of emotional difficulties among school students with T1D and variable levels of support from school staff to assist these students to manage their diabetes at school
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New therapeutic opportunities from dissecting the pre-B leukemia bone marrow microenvironmentWe provide evidence that targeting leukemia-induced bone loss is a therapeutic strategy for pre-B ALL
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High Dose Vitamin D supplementation alters faecal microbiome and predisposes mice to more severe colitisHigh dose vitamin D supplementation is associated with a shift to a more inflammatory faecal microbiome and increased susceptibility to colitis
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Out-of-Home Care and the Educational Achievement, Attendance, and Suspensions of Maltreated Children: A Propensity-Matched StudyOut-of-home care was not found to be a significant factor in the adverse educational outcomes of these children
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Candidate gene testing in clinical cohort studies with multiplexed genotyping and mass spectrometryWe describe a cost-effective tag single nucleotide polymorphism approach using a multiplexed genotyping assay with mass spectrometry