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Increased CTLA-4+ T cells may contribute to impaired T helper type 1 immune responses in patients with chronic obstructive pulmonary diseaseChronic inflammation may expand sub-populations of T cells expressing CTLA-4 in COPD patients and therefore impair T-cell function
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The 2015 Middle Childhood Survey (MCS) of mental health and well-being at age 11 years in an Australian population cohortmost children report mental health and well-being, but the population distribution spanned the full range of possible scores on every construct.
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Genotype and phenotype spectrum of NRAS germline variantsHere we describe 19 new cases with RASopathy due to disease-causing variants in NRAS
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The role of preschool quality in promoting child development: evidence from rural IndonesiaThis article examines the relationship between preschool quality and children’s early development in a sample of over 7900 children enrolled in 578 preschools in rural Indonesia.
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Somatosensory discrimination intervention improves body position sense and motor performance in children with hemiplegic cerebral palsyThe intervention group improved in goal performance, proprioception, and bimanual hand use and maintained improvement at 6-mo follow-up.
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IFNβ inhibits the development of allergen tolerance and is conducive to the development of asthma on subsequent allergen exposureData indicate a role for Interferonβ in linking viral infection and allergy
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Ultraviolet irradiation of skin alters the faecal microbiome independently of vitamin D in miceSkin exposure to ultraviolet radiation alters the faecal microbiome, and further investigations to explore the implications of this in health and disease are warranted
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Does the Risk Outweigh the Benefits? Adolescent Responses to Completing Health SurveysSelf-reported experiences of adolescents in population-based samples when completing health-related surveys on topics with varying potential for evoking distres
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Discovering the sense of touch: Protocol for a randomised controlled trial examining the efficacy of a intervention for children with cerebral palsyThis study will assess the efficacy of an intervention to increase somatosensory discrimination ability in children with cerebral palsy
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Latent profiles of early developmental vulnerabilities in a New South Wales child population at age 5 yearsPatterns of early childhood developmental vulnerabilities may provide useful indicators for particular mental disorder outcomes in later life