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Boosting the influenza vaccine schedule in children with cancer: a prospective open-label studyCurrent immunization guidelines recommend one dose of influenza vaccine for children aged ≥9 years and two doses for younger or vaccine-naïve children. However, children receiving chemotherapy have an attenuated immune response. We performed a prospective open-label study in children undergoing treatment for cancer at Perth Children's Hospital, Western Australia, to examine the safety and efficacy of a boosted influenza schedule.
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Immunogenicity and Safety of a 2 + 1 DTPa Priming Schedule in Australian Infants and the Impact of Maternally Derived Antibodies on Pertussis Antibody Responses up to 4 Years of AgeWe assessed the impact of maternally derived pertussis antibodies on infant responses to a 2 + 1 vaccine schedule (6 weeks, 12 weeks, and 12 months). Infants with baseline antibodies showed lower IgG responses following the primary vaccination series, but this did not impair booster responses at 4 years of age.
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Sex-specific associations between umbilical cord blood testosterone levels and language delay in early childhoodPreliminary evidence suggests that prenatal testosterone exposure may be associated with language delay.
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Emergency department overcrowding, mortality and the 4-hour rule in Western AustraliaThe objective of this study was to assess whether emergency department (ED) overcrowding was reduced after the introduction of the 4-hour rule in WA hospitals.
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Parental prenatal smoking and risk of childhood Acute Lymphoblastic LeukemiaThe association between parental smoking and risk of childhood acute lymphoblastic leukemia (ALL) was investigated in an Australian population-based...
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Pandemic influenza H1N1 2009 infection in Victoria, AustraliaConflicting findings regarding the level of protection offered by seasonal influenza vaccination against pandemic influenza H1N1 have been reported.
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Crowding and other strong predictors of upper respiratory tract carriage of otitis media-relatedWe investigated predictors of nasopharyngeal carriage in Australian Aboriginal and non-Aboriginal children.
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Western Australian children with acute lymphoblastic leukemia are taller at diagnosis than unaffected children of the same age and sexAcute lymphoblastic leukemia (ALL) is the commonest childhood malignancy in Australian children
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Linking MECP2 and pain sensitivity: the example of Rett syndromeThis study investigated the nature and prevalence of atypical pain responses in Rett syndrome and their relationships with specific MECP2 mutations.
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Representativeness of child controls recruited by random digit diallingRecruiting control subjects who are representative of the population from which the cases are drawn is a challenge in case-control studies