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Prevention of Allergy/Asthma - New StrategiesThis review focuses on the scientific rationale for early intervention aimed at asthma prophylaxis and discusses therapeutic approaches
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Distinguishing benign from pathologic TH2 immunity in atopic childrenIn addition to its role in blocking TH2 effector activation in the late-phase allergic response, IL-10 is a known IgG1 switch factor
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Airway epithelial repair in health and disease: Orchestrator or simply a player?This review attempts to highlight migration-specific and cell-extracellular matrix (ECM) aspects of repair used by epithelial cells
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Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responsesDifferential network analysis of allergen-induced CD4 T cell responses can unmask covert disease-associated genes and pin point novel therapeutic targets
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Pressurised metered dose inhaler-spacer technique in young children improves with video instructionRepeated video instruction over time improves inhaler technique in young children
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Environmental microbial exposure and protection against asthmaThis article looks at the clinical implications of the research into microbial exposure & protection against asthma.
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Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infantsThe purpose of this article is to highlight emerging evidence for existing allergy prevention guidelines regarding potential benefits of supporting early...
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Disruption of β-catenin/CBP signaling inhibits human airway epithelial-mesenchymal transition and repair.The airway epithelium of both children and adults with asthma is relatively undifferentiated characterized by a significantly increased proportion of...
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Chronic cat allergen exposure induces a Th2 cell-dependent IgG4 response related to low sensitizationThis study evaluated the relationship between cat allergen–specific biomarkers in adults with cat allergy with and without cat ownership.
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Environmental Factors in Children's Asthma and Respiratory EffectsAsthma is more common in childhood than in adulthood and is more correctly thought of as a syndrome than as a discrete condition.