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Research

Simultaneous Targeting of DNA Replication and Homologous Recombination in Glioblastoma with a Polyether Ionophore

Our findings highlight the potential of salinomycin to induce DNA lesions and inhibit homologous recombination to greatly enhance the effect of radiotherapy

Research

Examining parent use of specific intervention techniques during a 12-week training program based on the Early Start Denver Model

This study included five mothers of young children with autism who participated in a 12-week parent training program based on the Early Start Denver Model

Research

Children's neighbourhood physical environment and early development: an individual child level linked data study

The neighbourhood physical environment has a weak but significant association with early childhood development

Research

Impact of HIV and antiretroviral drug exposure on lung growth and function over 2 years in an African Birth Cohort

HIV exposure is associated with altered lung function in early life, with a vulnerable HIV-exposed uninfected subgroup based on maternal disease severity

Research

Lessons learned in genetic research with Indigenous Australian participants

We reflect on the lessons learned from a recent genome‐wide association study of rheumatic heart disease with Aboriginal Australian participants

Research

The impact of new universal child influenza programs in Australia: Vaccine coverage, effectiveness and disease epidemiology in hospitalised children in 2018

A significant reduction in severe influenza was observed in Australian children, possibly contributed to by improved vaccine coverage and high vaccine effectiveness

Research

Low-dose UV radiation before running wheel access activates brown adipose tissue

When combined with physical activity, low-dose UVR may more effectively limit adiposity and modulate metabolic and immune pathways in iBAT

Research

Reference exome data for Australian Aboriginal populations to support health-based research

Our data set provides a useful reference point for genomic studies on Aboriginal Australians

Research

Combination of clinical symptoms and blood biomarkers can improve discrimination between bacterial or viral community-acquired pneumonia in children

Combining elevated CRP with the presence or absence of clinical signs/ symptoms differentiates definite bacterial from presumed viral pneumonia better than CRP alone