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Toll-like receptor 7 function is reduced in adolescents with asthmaAnti-viral innate immune responses may be impaired in asthma, although the mechanisms are not well understood.
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Assessment of the potency and potential immunomodulatory effects of the Measles Mumps Rubella-Varicella vaccine in infantsThis study compared the potency and immunomodulatory effects of measles mumps rubella (MMR) vaccine given to infants alone or in combination with varicella...
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Asthma: Acute asthma flare-up in school-age childrenThe aim of this study is to identify differences in immune cells that are involved in the disease.
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Immunobiology & Immunotherapeutic ProgramListed are The Kids Research Institute Australia research teams involved in our Immunity and Inflammation Program. This program sits under the Early Environment research theme.
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The mechanism or mechanisms driving atopic asthma initiation: The infant respiratory microbiome moves to center stageAlthough debate surrounding the mechanism or mechanisms governing this causal pathway remains intense, demonstration of the capacity of pretreatment...
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Meta-analysis identifies seven susceptibility loci involved in the atopic marchEczema often precedes the development of asthma in a disease course called the 'atopic march'.
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Global allergy forum and second davos declaration 2013 allergy: Barriers to cure - Challenges and actions to be takenThe epidemic increase in the prevalence of allergic disease, which first started in the industrialized countries in the 1960s, may have reached a peak in the...
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Childhood atopy and mental health: a prospective, longitudinal investigationFindings are the first linking atopy (measured by both parent report and objective verification) with increased vulnerability to affective and anxiety problems
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Ontogeny of toll-like and NOD-like receptor-mediated innate immune responses in Papua New Guinean infantsStudies addressing the ontogeny of the innate immune system in early life have reported mainly on Toll-like receptor (TLR) responses in infants living in...