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Variants associated with HHIP expression have sex-differential effects on lung functionLung function is highly heritable and differs between the sexes throughout life. However, little is known about sex-differential genetic effects on lung function. We aimed to conduct the first genome-wide genotype-by-sex interaction study on lung function to identify genetic effects that differ between males and females.
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Bronchopulmonary dysplasia: Rationale for a pathophysiological rather than treatment based approach to diagnosisThis review describes the evolution of bronchopulmonary dysplasia definitions, evaluates the benefits and limitations of each approach
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Association between diesel engine exhaust exposure and lung function in Australian gold minersDiesel engine exhaust exposures were higher in underground miners and had a negative association with their lung function over a single 12-h shift
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Altered lung structure and function in mid-childhood survivors of very preterm birthTo obtain comprehensive data on lung structure and function in mid-childhood from survivors of preterm birth.
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Air trapping in early cystic fibrosis lung disease-Does CT tell the full story?Mosaic attenuation on expiratory chest computed tomography (CT) is common in early life cystic fibrosis (CF) and often referred to as "air trapping"
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Lung function in African infants: A pilot studyUnsedated infant lung function measures of tidal breathing, MBW, and eNO are feasible in a semi-rural African setting
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Nasal airway epithelial repair after very preterm birthNasal epithelial cells from very preterm infants have a functional defect in their ability to repair beyond the first year of life, and failed repair may be associated with antenatal steroid exposure.
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Lung function in African infants: A pilot studyInfant lung function (ILF) testing may provide useful information about lung growth and susceptibility to respiratory disease.
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Respiratory impedance and bronchodilator responsiveness in healthy children aged 2-13 yearsThere is limited information on changes in FOT outcomes in healthy children beyond the preschool years and the level of bronchodilator responsiveness (BDR)...
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MetaNeb Versus Usual Care During Exacerbations of Cystic Fibrosis: An RCTDuring exacerbations, when symptom and treatment burden are increased, individuals with cystic fibrosis (CF) are likely to prefer airway clearance techniques (ACTs) that require minimal effort. Therefore, in adults with CF who were hospitalised with an exacerbation, we sought to compare the effect of the MetaNeb with usual ACTs on respiratory function and expectorated sputum.