Search
This project investigates how cells of the immune system respond to substances to cause allergies to help develop new treatments.
Rothwell Family Fellow; Head, Airway Epithelial Research
Asthma is a chronic disease of the airways, most commonly driven by immuno-inflammatory responses to ubiquitous airborne antigens.
Sex-related differences in bronchial hyperresponsiveness (BHR) have been reported in adolescents, but the mechanisms remain obscure.
The airway epithelium forms a highly regulated physical barrier that normally prevents invasion of inhaled pathogens and allergens from the airway lumen.
Atopic asthma is the most common form of asthma, particularly during childhood, and in many cases it persists into adult life.
Vitamin D has been linked in some studies with atopy- and asthma-associated phenotypes in children with established disease,but its role in disease inception...
Characterization of the complete IgE binding spectrum of cat allergens is important for the development of improved diagnosis and effective immunotherapeutics.
Interleukin-10 is a key immunomodulatory cytokine the principal function of which is to limit the magnitude of immune response.
A new and potentially more pathogenic group of human rhinovirus (HRV), group C (HRVC), has recently been discovered.