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Real world effectiveness of early ensitrelvir treatment in patients with SARS-CoV-2, a retrospective case seriesEnsitrelvir, a 3C-like protease inhibitor, received emergency approval in Japan in November 2022 for treating non-hospitalized patients with mild-to-moderate COVID-19. However, confirmation of its real-world clinical effectiveness is limited.
Research
Comparison of rhinovirus antibody titers in children with asthma exacerbations and species-specific rhinovirus infectionAsthma exacerbations are associated with human rhinovirus (HRV) infections, and more severe exacerbations are associated with HRV-C.
Research
Respiratory allergen from house dust mite is present in human milk and primes for allergic sensitization in a mouse model of asthmaThese data highlight that antigen administration to the neonate through the oral route may contribute to child allergic sensitization and have important...
Research
Novel drug targets for asthma and COPD: Lessons learned from in vitro and in vivo modelsThis paper is a review of potential novel therapeutic targets or tools for the treatment of asthma and COPD.
Research
Transcription factor p63 regulates key genes and wound repair in human airway epithelial Basal cellsThe airway epithelium in asthma displays altered repair and incomplete barrier formation.
News & Events
NHMRC funding awarded to support child health researchThe Kids Research Institute Australia researchers have been awarded more than $10 million in research funding from the National Health and Medical Research Council (NHMRC).
News & Events
Switch on the immune system earlyFindings by Professor Pat Holt revealed researchers had been heading down the wrong path in their battle strategy against respiratory allergy and asthma.
News & Events
Overseas trip will help unlock the asthma puzzleOne in ten Australians have asthma and Dr Kimberley Wang from The Kids Research Institute Australia is on a mission to find out what causes it.
News & Events
Volunteers needed for world-first trial to prevent asthmaAustralian scientists have today launched a world first research trial into a treatment that could prevent asthma in high risk children.
Research
IgE and IgG binding patterns and T-cell recognition of fel d 1 and Non-Fel d 1 cat allergensTo compare IgE and IgG antibody binding and T-cell recognition of the major cat allergen Fel d 1 with other cat proteins with known IgE binding properties.