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Quantifying airway remodelling for research or clinical purposes: How should we normalize for airway size?

Citation: Donovan GM, Wang KCW, Elliot JG, James AL, Noble PB. Quantifying airway remodelling for research or clinical purposes: How should we

Airway-associated adipose tissue accumulation is increased in a kisspeptin receptor knockout mouse model

Airway-associated adipose tissue increases with body mass index and is a local source of pro-inflammatory adipokines that may contribute to airway pathology in asthma co-existing with obesity. Genetic susceptibility to airway adiposity was considered in the present study through kisspeptin/kisspeptin receptor signalling, known to modulate systemic adiposity and potentially drive airway remodelling. 

Identifying the asthma research priorities of people with asthma, their carers and other stakeholders

People living with asthma, their carers, clinicians and policymakers are the end-users of research and need research that address their individual healthcare needs. We aimed to understand the research priorities of end-users of asthma research.

BCG-Induced Immune Training: Interplay between Trained Immunity and Emergency Granulopoiesis

Bacille Calmette-Guérin (BCG) is the most commonly administered vaccine in human history. The medical application of BCG extends far beyond the fight against tuberculosis. Despite its stellar medical record over 100 years, insight into how BCG provides this vast range of benefits is largely limited, both for its pathogen-specific (tuberculosis) as well as pathogen-agnostic (other infections, autoimmunity, allergies, and cancer) effects.

My child is wheezing – what should I do?

Almost 50 per cent of preschool children will experience at least one episode of wheeze, a whistling sound produced by the airways during breathing.

Can a simple urine test predict asthma? New study aims to find out

The Kids Research Institute Australia researchers are investigating whether a simple urine test could predict whether young children with wheezing symptoms will go on to develop asthma.

Very preterm babies at risk of declining lung function throughout childhood

A The Kids Research Institute Australia study published in The Lancet Child & Adolescent Health has found that survivors of very preterm birth face declining lung function

The Kids researchers awarded Raine Medical Research Foundation funding

Congratulations to Dr Gail Alvares and Dr Rachel Foong, who have been awarded funding from the Raine Medical Research Foundation.

National Asthma Week: 10 things you need to know about asthma

Asthma affects about half a million Australian children and is one of the most common reasons why kids need to see a doctor or go to emergency.

State Government boost for The Kids research

The Kids Research Institute Australia researchers have been awarded five of eight State Government awards designed to help cover the hidden costs of conducting research.