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The way the immune system operates differs between males and females. This is due to both differential expression of immune-related genes from the sex chromosomes as well as the immune modulatory properties of sex hormones. Together, these effects contribute to a skewed prevalence of disease and disease course between males and females, including allergic-, infectious-, autoimmune-, and cancerous disease.
Asthma is among the commonest noncommunicable diseases of childhood and often occurs with other atopic comorbidities. A previous case-control study found evidence that compared to children who received acellular pertussis (aP) vaccines in early infancy, children who received one or more doses of whole-cell pertussis (wP) vaccine had lower risk of developing IgE-mediated food allergy. We hypothesized that wP vaccination in early infancy might protect against atopic asthma in childhood.
Healthy lungs help you to breathe better. This means you can sleep better, as well as play sports, run and walk without being short winded.
Rothwell Family Fellow; Head, Airway Epithelial Research
In this study, using a mouse model, we determined whether vitamin D deficiency in utero and during early life modulated the severity of asthma.
Population-based birth cohorts on asthma and allergies increasingly provide new insights into the development and natural history of the diseases.
Researchers at The Kids Research Institute Australia have found children with vitamin D deficiency are more likely to develop asthma.
Join us for our Annual Community Lecture entitled "You Are What You Breathe" with Professor Stephen Holgate.
Australia has one of the highest burdens of asthma in the world. In this video, two Perth families share their story of raising children with the respiratory co
Michelle has spent countless nights watching her son struggle to breathe. Our researchers are working to find better treatments for kids living with asthma.