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This study investigates the impact of measuring adherence and providing feedback on medication usage by children with unstable asthma.
This study aimed to investigate the effects of different macro-environments on asthma genotype-phenotype associations in 2 geographically separated populations
Anti-viral innate immune responses may be impaired in asthma, although the mechanisms are not well understood.
One of the major challenges in health studies with a spatial dimension is to produce valid and meaningful geographical representations of risk.
The aims of this study were to investigate kinin receptor expression on eosinophils of asthmatic and healthy subjects
In this study, we examined the effects of maternal smoking as a major adverse exposure in early life, on mucosal immune function and allergen sensitization...
There is intense interest in the interaction between microbial compounds and allergy.
The Airway Epithelial Research Team is investigating the role of the epithelium in the development of airway diseases including asthma, cystic fibrosis and lung transplant rejection.
Asthma is among the commonest noncommunicable diseases of childhood and often occurs with other atopic comorbidities. A previous case-control study found evidence that compared to children who received acellular pertussis (aP) vaccines in early infancy, children who received one or more doses of whole-cell pertussis (wP) vaccine had lower risk of developing IgE-mediated food allergy. We hypothesized that wP vaccination in early infancy might protect against atopic asthma in childhood.
Airway-associated adipose tissue increases with body mass index and is a local source of pro-inflammatory adipokines that may contribute to airway pathology in asthma co-existing with obesity. Genetic susceptibility to airway adiposity was considered in the present study through kisspeptin/kisspeptin receptor signalling, known to modulate systemic adiposity and potentially drive airway remodelling.