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Is Streptococcus pyogenes resistant or susceptible to trimethoprim- sulfamethoxazole?Streptococcus pyogenes is commonly believed to be resistant to trimethoprim-sulfamethoxazole (SXT), resulting in reservations about using SXT for skin and...

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Professor Jonathan Carapetis AMInstitute Director; Head, Strep A Translation; Co-Founder of REACH

Research
Co-Designing Health Service Evaluation Tools That Foreground First Nation Worldviews for Better Mental Health and Wellbeing OutcomesIt is critical that health service evaluation frameworks include Aboriginal people and their cultural worldviews from design to implementation. During a large participatory action research study, Elders, service leaders and Aboriginal and non-Aboriginal researchers co-designed evaluation tools to test the efficacy of a previously co-designed engagement framework. Through a series of co-design workshops, tools were built using innovative collaborative processes that foregrounded Aboriginal worldviews.
Research
Missing Piece Study protocol: Prospective surveillance to determine the epidemiology of group A streptococcal pharyngitis and impetigo in remote Western AustraliaGroup A β-haemolytic Streptococcus (GAS), a Gram-positive bacterium, causes skin, mucosal and systemic infections. Repeated GAS infections can lead to autoimmune diseases acute rheumatic fever (ARF) and rheumatic heart disease (RHD). Aboriginal and Torres Strait Islander peoples in Australia have the highest rates of ARF and RHD in the world.
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Preventing heart failure: a position paper of the Heart Failure Association in collaboration with the European Association of Preventive CardiologyThe heart failure epidemic is growing and its prevention, in order to reduce associated hospital readmission rates and its clinical and economic burden, is a key issue in modern cardiovascular medicine. The present consensus document aims to provide practical evidence-based information to support the implementation of effective preventive measures.
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Towards a diagnostic test for rheumatic feverGlenn Jonathan Michael Pat Tim Tobias Pearson Carapetis AM Serralha Holt Barnett Kollmann BA (Education) PhD Candidate AM MBBS FRACP FAFPHM PhD FAHMS
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What risk does underlying trimethoprim resistance pose for the development of cotrimoxazole-resistant skin infectionsTim Barnett PhD Head, Strep A Pathogenesis and Diagnostics timothy.barnett@thekids.org.au Head, Strep A Pathogenesis and Diagnostics Tim has worked
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Missing voices: Profile and extent of acquired communication disorders in Aboriginal and non-Aboriginal adult stroke survivors in Western AustraliaThe needs of Aboriginal stroke patients with acquired communication disorder should inform appropriate service design for speech pathology and rehabilitation
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Pediatric sepsis in the developing world.Sepsis is the leading killer of children worldwide, but this is not reflected in estimates of global mortality.