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Drug-resistant gram-negative bacterial infections in children in the Oceania region: review of the epidemiology, antimicrobial availability, treatment, clinical trial and pharmacokineticGram-negative bacterial infections remain a major cause of morbidity and mortality in children and neonates globally, compounded by the rise of antimicrobial resistance. Barriers to paediatric antibiotic licencing lead to reduced availability of potentially effective agents for treatment. For children and neonates in the Oceania region, specific challenges remain including a paucity of surveillance data on local rates of antimicrobial resistance, and lack of availability of newer, more costly agents.
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High concentrations of middle ear antimicrobial peptides and proteins are associated with detection of middle ear pathogens in children with recurrent acute otitis mediaElevated antimicrobial proteins and peptides and cytokines in middle ear effusion are a marker of inflammation and bacterial persistence
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Disparities between Aboriginal and non-Aboriginal perinatal mortality rates in Western Australia from 1980 to 2015This study aimed to examine the pattern of stillbirth and neonatal mortality rate disparities over time in Western Australia
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Maternal Fiber Dietary Intakes during Pregnancy and Infant Allergic DiseaseMaternal resistant starch consumption was differentially associated with infant phenotypes, with reduced risk of infant wheeze, but increased risk of eczema
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Golden Age of Medicine 2.0: Lifestyle Medicine and Planetary Health PrioritizedWe emphasize that barriers to planetary health and the clinical application of lifestyle medicine are maintaining an unhealthy status quo
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Trends in mental health related contacts among mothers of Aboriginal children in Western Australia (1990-2013)Many of the mental health issues that women develop earlier in life are chronic at the time of conception, during pregnancy and at birth
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A Qualitative Exploration of the Role and Needs of Classroom Teachers in Supporting the Mental Health and Well-Being of Deaf and Hard-of-Hearing ChildrenThis study aimed to explore the role of schools and classroom teachers in supporting the mental health and well-being of deaf and hard of hearing children
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Mechanical Abnormalities of the Airway Wall in Adult Mice After Intrauterine Growth RestrictionWe propose that mechanical abnormalities of the airway wall acquired through disrupted fetal growth impact susceptibility to disease
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Telling an Adult at School about Bullying: Subsequent Victimization and Internalizing ProblemsTo prevent persistent victimization, schools and teachers need to be better equipped to respond effectively when a student first becomes a target of bullying
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A new strategy for vascular complications in young people with type 1 diabetes mellitusThese findings present an opportunity to move towards the personalized care of adolescents with type 1 diabetes mellitus