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Research

Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses

Differential network analysis of allergen-induced CD4 T cell responses can unmask covert disease-associated genes and pin point novel therapeutic targets

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Developments in the field of allergy in 2014 through the eyes of Clinical and Experimental Allergy

The pathogenesis of asthma continues to be a major topic of interest to our authors with reviews and original papers on the role of viruses, mechanisms of...

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Suppression of adrenomedullin contributes to vascular leakage and altered epithelial repair during asthma

The anti-inflammatory peptide, adrenomedullin (AM), and its cognate receptor are expressed in lung tissue, but its pathophysiological significance in airway...

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Probiotics for treatment and primary prevention of allergic diseases and asthma: looking back and moving forward

Review treatment and primary prevention studies, recent meta-analyses, and discuss the current understanding of the role of probiotics in this context

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Comparison of rhinovirus antibody titers in children with asthma exacerbations and species-specific rhinovirus infection

Asthma exacerbations are associated with human rhinovirus (HRV) infections, and more severe exacerbations are associated with HRV-C.

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Respiratory allergen from house dust mite is present in human milk and primes for allergic sensitization in a mouse model of asthma

These data highlight that antigen administration to the neonate through the oral route may contribute to child allergic sensitization and have important...

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IgE and IgG binding patterns and T-cell recognition of fel d 1 and Non-Fel d 1 cat allergens

To compare IgE and IgG antibody binding and T-cell recognition of the major cat allergen Fel d 1 with other cat proteins with known IgE binding properties.

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Longer duration of exclusive breastfeeding associated with reduced risk of childhood asthma up to age six

Breastfeeding is recommended for all infants irrespective of atopic heredity, although epidemiological studies provide conflicting results in this debate.

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Transcription factor p63 regulates key genes and wound repair in human airway epithelial Basal cells

The airway epithelium in asthma displays altered repair and incomplete barrier formation.