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Digit ratio (2D:4D) is widely used as a marker of prenatal androgen exposure
There is a growing understanding that chronic respiratory diseases in adults have their origins in early life
Epidemiologic associations between viral lower respiratory infections (LRIs) and asthma in later childhood are well known
Asthma is a chronic inflammatory disease of the small and large conducting airway mucosa characterised by Th2 cell immunity.
We sought to assess whether the trajectory to asthma begins already at birth and whether epigenetic mechanisms, contribute to asthma inception.
High fractional exhaled nitric oxide and sputum eosinophils are associated with an increased risk of future virus-induced exacerbations.
We aimed to quantify the diagnostic utility of mannitol challenge testing for asthma in a community cohort and a symptomatic wheezing subset of this cohort.
In this study, we aimed to use microRNAs-which are critical regulators of signaling cascades-to identify so far uncharacterized asthma pathogenesis pathways
Recurrent severe asthma exacerbations are associated with decreased lung growth or accelerated loss of long function and add substantially to cost and morbidity
Our results indicate a dissociation between the antibody and T-cell responses to rhinoviruses