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Research

Spatial analysis of hepatobiliary abnormalities in a population at high-risk of cholangiocarcinoma in Thailand

Cholangiocarcinoma (CCA) is a serious health challenge with low survival prognosis. The liver fluke, Opisthorchis viverrini, plays a role in the aetiology of CCA, through hepatobiliary abnormalities: liver mass (LM), bile duct dilation, and periductal fibrosis (PDF). A population-based CCA screening program, the Cholangiocarcinoma Screening and Care Program, operates in Northeast Thailand. Hepatobiliary abnormalities were identified through ultrasonography.

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Associations Among Early Stimulation, Stunting, and Child Development in Four Countries in the East Asia–Pacific

This study examined associations among preschool attendance, home learning activities, stunting status, and early child development using data from the validation study of the East Asia–Pacific Early Child Development Scales (EAP-ECDS).

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An international cohort study of birth outcomes associated with hospitalized acute respiratory infection during pregnancy

Acute respiratory or febrile illness hospitalization during pregnancy was associated with increased risk of preterm birth and low birthweight birth

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Asbestos-related diseases

The main issues that led to the ban on asbestos in industry are those of malignancy: lung cancer, malignant mesothelioma of the pleura and of the peritoneum

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Spatial and temporal patterns of dengue incidence in Bhutan: a Bayesian analysis

This study aimed to quantify the spatial and temporal patterns of dengue and their relationship to environmental factors in dengue-affected areas

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SMART Work Design: Accelerating the Diagnosis of Rare Diseases in the Western Australian Undiagnosed Diseases Program

The accurate and efficient diagnosis of rare diseases, many of which include congenital anomalies, depends largely on the specialists who diagnose them - including their ability to work alongside specialists from other fields and to take full advantage of cutting-edge precision medicine technologies and precision public health approaches.

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Risk of Hospitalizations Following Gastrostomy in Children with Intellectual Disability

Gastrostomy was associated with health benefits including reduced all-cause and epilepsy hospitalizations, but was not protective against acute LRTI

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Prevalence of Motor Difficulties in Autism Spectrum Disorder: Analysis of a Population-Based Cohort

In this population-based cohort that included 2,084 children with autism aged ≤6 years, over one-third met the criteria for motor difficulties

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Racial discrimination and child and adolescent health in longitudinal studies: A systematic review

This review emphasises the need to gain evidence for the mechanisms linking early racism exposure to adverse health outcomes in later life

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Timeliness of signal detection for adverse events following influenza vaccination in young children: a simulation case study

Active vaccine safety surveillance leading to rapid detection of a safety signal would likely have resulted in earlier suspension of Fluvax from the vaccination programme