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Research
Home pesticide exposures and risk of childhood leukemia: Findings from the childhood leukemia international consortiumIn this investigation, the authors found an association between home pesticide exposure before birth and during a child's early years and acute lymphoblastic...
Research
Home paint exposures and risk of childhood acute lymphoblastic leukemia: findings from the Childhood Leukemia International ConsortiumThis paper demonstrated that home paint exposure shortly before conception, during pregnancy, and/or after birth appeared to increase the risk of childhood ALL.
Research
Increased Body Mass Index during Therapy for Childhood Acute Lymphoblastic Leukemia: A Significant and Underestimated ComplicationWe undertook a retrospective review of children diagnosed with acute lymphoblastic leukemia (ALL) and treated with modern COG protocols to determine...
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New clinical trial to improve outcomes for babies with leukaemiaThe Australian arm of an international clinical trial looking at improved treatments for young babies with leukaemia has been awarded funding from the MRFF.
Research
Invasive fungal disease and antifungal prophylaxis in children with acute leukaemia: a multicentre retrospective Australian cohort studyInvasive fungal disease (IFD) is a common and important complication in children with acute myeloid leukaemia (AML). We describe the epidemiology of IFD in a large multicentre cohort of children with AML.
News & Events
New study exposes link between pesticides and childhood brain tumoursA new Telethon Institute study has revealed a potential link between pesticide treatments in the home and a higher risk of children developing brain tumours.
News & Events
Exposure to diesel exhaust increases risk of child brain tumoursResearch at Telethon Institute has shown a correlation between brain tumours in young children and their parents' exposure to diesel exhaust fumes before birth.
News & Events
Researchers find new insight into genetics of aggressive cancerResearchers at Telethon Institute have found genetic differences in the rare and aggressive NUT-midline carcinoma, presenting new treatment opportunities.
Research
Maternal folate and other vitamin supplementation during pregnancy and risk of acute lymphoblastic leukemia in the offspringThe Australian Study of Causes of Acute Lymphoblastic Leukemia in Children (Aus-ALL) was designed to test the hypothesis, raised by a previous Western Australia
Research
Combining CRISPR-Cas9 and TCR exchange to generate a safe and efficient cord blood-derived T cell product for pediatric relapsed AMLHematopoietic cell transplantation (HCT) is an effective treatment for pediatric patients with high-risk, refractory, or relapsed acute myeloid leukemia (AML). However, a large proportion of transplanted patients eventually die due to relapse. To improve overall survival, we propose a combined strategy based on cord blood (CB)-HCT with the application of AML-specific T cell receptor (TCR)-engineered T cell therapy derived from the same CB graft.