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Measuring disease and injury burden in populations requires a composite metric that captures both premature mortality and the prevalence and severity of...

Non-fatal health outcomes from diseases and injuries are a crucial consideration in the promotion and monitoring of individual and population health.

The current prophylactic treatment to prevent rheumatic heart disease requires four-weekly intramuscular injection of a suspension of the poorly soluble benzathine salt form of penicillin G (BPG) often for more than 10 years. In seeking to reduce the frequency of administration to improve adherence, biodegradable polymer matrices have been investigated.

Scabies and impetigo are common in Timor-Leste, with very high prevalence of scabies in the rural district of Ermera

Prevalence of skin sores and scabies in remote Australian Aboriginal communities remains unacceptably high, with Group A Streptococcus (GAS) the dominant pathogen. We aim to better understand the drivers of GAS transmission using mathematical models.

The rates of RHD in Timor-Leste are among the highest in the world, and prevalence is higher among girls than boys. Community engagement is essential for ensuring follow-up and the effective delivery of secondary prophylaxis.

Diarrhoeal disease is the second leading cause of death in children under 5 years globally, killing 525 000 annually. Australian Aboriginal and Torres Strait Islander (hereafter Aboriginal) children suffer a high burden of disease.

Rheumatic heart disease (RHD) is a chronic cardiac condition with an infectious aetiology, causing high disease burden in low-income settings.

The choice of RHD is telling: the disease is a marker of inequality, a novel lens for considering health systems and a feasible target for disease control.

We estimated the global disease prevalence of and mortality due to rheumatic heart disease over a 25-year period