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Research

Global epidemiology of valvular heart disease

Valvular heart disease is a major contributor to loss of physical function, quality of life and longevity. The epidemiology of VHD varies substantially around the world, with a predominance of functional and degenerative disease in high-income countries, and a predominance of rheumatic heart disease in low-income and middle-income countries. Reflecting this distribution, rheumatic heart disease remains by far the most common manifestation of VHD worldwide and affects approximately 41 million people.

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Protocol for the systematic review of the epidemiology of superficial Streptococcal A infections (skin and throat) in Australia

We have produced a protocol for the comprehensive systematic review of the current literature around superficial group A Streptococcal infections in Australia.

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The full health, economic, and social benefits of prospective Strep A vaccination

Recent research has documented a wide range of health, economic, and social benefits conferred by vaccination, beyond the direct reductions in morbidity, mortality, and future healthcare costs traditionally captured in economic evaluations.

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Public health and economic perspectives on acute rheumatic fever and rheumatic heart disease

Efforts to eliminate ARF and RHD in Australia over the past decade have so far been unsuccessful, but this can change

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Burden of cardiovascular diseases in the Eastern Mediterranean Region, 1990-2015: findings from the Global Burden of Disease 2015 study

The age-standardized disability-adjusted life years rates in the Eastern Mediterranean Region are considerably higher than the global average.

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How many doses make a difference? An analysis of secondary prevention of rheumatic fever and rheumatic heart disease

increased adherence to penicillin prophylaxis is associated with reduced acute rheumatic fever recurrence and a likely reduction in mortality

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Scabies and risk of skin sores in remote Australian Aboriginal communities: A self-controlled case series study

The association between scabies and skin sores is highly significant and indicates a causal relationship

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Ascertaining infectious disease burden through primary care clinic attendance among young Aboriginal children living in four remote communities in Western Australia

Improved public health measures targeting bacterial skin infections are needed to reduce this high burden of skin infections in Western Australia