Search
Research
X-Linked Hypophosphataemia and Burosumab: A Systemic Disease With a New TreatmentX linked hypophosphataemia (XLH) is a systemic, chronic condition that significantly impairs quality of life. In XLH, a phosphate regulating endopeptidase homologue X-linked (PHEX) gene mutation leads to excess fibroblast growth factor 23 (FGF23), causing hypophosphataemia and subsequent rickets, lower limb deformity, pain and other sequelae, however there are likely other non-FGF23 mediated mechanisms contributing to disease
Research
Disparities in Diabetes Technology Uptake in Youth and Young Adults With Type 1 Diabetes: A Global PerspectiveGlobally, nearly 9 million people are living with type 1 diabetes (T1D). Although the incidence of T1D is not affected by socioeconomic status, the development of complications and limited access to modern therapy is overrepresented in vulnerable populations. Diabetes technology, specifically continuous glucose monitoring and automated insulin delivery systems, are considered the gold standard for management of T1D, yet access to these technologies varies widely across countries and regions, and varies widely even within high-income countries.
Research
Real-world glycaemic outcomes in children and young people on advanced hybrid closed-loop therapy: A population-based study in Western AustraliaTo evaluate real-world glycaemic outcomes in children with type 1 diabetes commencing advanced hybrid closed loop therapy and to explore these outcomes based on the cohort's clinical and socioeconomic characteristics.
Research
The usability and feasibility of a self-compassion chatbot (COMPASS) for youth living with type 1 diabetesAlthough it is well established that youth with type 1 Diabetes (T1D) experience high rates of distress, current clinical care is often under-resourced and unable to provide sufficient or timely psychological support. The current study was designed to evaluate the safety, usability and feasibility of 'COMPASS,' a self-compassion chatbot intervention.
Research
Comparable glycemic outcomes for pediatric type 1 diabetes patients in metropolitan and non-metropolitan regions of Western Australia: A population-based studyThis study reports similar glycemic outcomes for patients attending diabetes clinics in metropolitan and non-metropolitan areas of WA
Research
Defining relevant hypoglycemia measures in children and adolescents with type 1 diabetesAs the choices of therapies in diabetes care multiply, it is essential to standardize the approach to measuring and recording hypoglycemia risk
Research
Performance of medtronic hybrid closed-loop iterations: Results from a randomized trial in adolescents with type 1 diabetesThis study investigates the performance of an iteration of the Medtronic hybrid closed-loop algorithm
Research
Insulin Pump Therapy in Adolescents With Very Poor Glycemic Control During a 12-Month Cohort TrialWe conclude that insulin pump therapy can be an effective tool to improve glycemic control in adolescents with long-standing treatment resistance
Research
Clinical characteristics of Western Australian children diagnosed with type 2 diabetes before 10 years of ageWe aimed to describe the characteristics of Western Australian children aged less than 10 years diagnosed with type 2 diabetes between June 2000 and June 2017
Research
Distinct Gut Virome Profile of Pregnant Women With Type 1 Diabetes in the ENDIA StudyFindings provide novel insight into the composition of the gut virome during pregnancy and demonstrate a distinct profile of viruses in women with type 1 diabetes