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Bacille Calmette-Guérin vaccine reprograms human neonatal lipid metabolism in vivo and in vitro

Vaccines have generally been developed with limited insight into their molecular impact. While systems vaccinology enables characterization of mechanisms of action, these tools have yet to be applied to infants, who are at high risk of infection and receive the most vaccines. Bacille Calmette-Guérin (BCG) protects infants against disseminated tuberculosis (TB) and TB-unrelated infections via incompletely understood mechanisms.

Severity of Rotavirus-Vaccine-Associated Intussusception: Prospective Hospital-Based Surveillance, Australia, 2007-2018

Multiple studies have shown an association between intussusception (IS) and receipt of monovalent or pentavalent rotavirus vaccine (RV) in the previous 21 days. Disease severity is an important consideration for risk-benefit evaluations of RV, but no studies have compared the severity of IS within 21 days of vaccination (vaccine-associated, VA) and later (not temporally-associated, VNA).

Real world impact of 13vPCV in preventing invasive pneumococcal pneumonia in Australian children: A national study

We aimed to assess the direct protective effect of 13 valent pneumococcal conjugate vaccine (13vPCV) against invasive pneumococcal pneumonia (IPP; including pneumonia and empyema) in children using a nation-wide case-control study across 11 paediatric tertiary hospitals in Australia.

Immunisation advice before, during and after pregnancy

Are you pregnant or planning to have a baby? There are important vaccinations that you should consider to protect your health and the health of your baby.

The Kids Research Institute Australia researcher awarded support funding

A Kids Research Institute Australia researcher has been awarded $10,000 from the New Independent Researcher Infrastructure Support (NIRIS) award.

Vaccination timing essential

We all know how important it is to vaccinate a child against harmful diseases but vaccinating a child at the right wrong age can cost lives.

Community Conversation- Infectious Diseases in Children

Consumers and community members are invited to join us to provide input into our childhood infectious diseases research.

National Indigenous Immunisation Research Workshop

You are invited to register to attend the National Indigenous Immunisation Research Workshop 2013: lessons learnt and future directions Workshop.

New vaccine could protect against more types of cancer-causing HPV

Trial of new vaccine that could provide women with additional protection against Human Papillomavirus (HPV) types known to cause cervical cancer.

Advancing the management and control of typhoid fever: a review of the historical role of human challenge studies

Improved understanding of Salmonella Typhi infection can help accelerate the development of improved vaccines and diagnostic tests necessary for disease control