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To date there have been relatively few studies on genetic determinants of susceptibility to neonatal infection and many of these have methodological...
Using data from three large-scale genetic association studies we compared recruitment strategy and sample return rates.
The interaction between genotype and Epstein Barr virus emerges as relevant for multiple sclerosis etiology.
The relationship between early life episodes of otitis media and later behavioural development with adjustment for confounders.
Our results provide a possible functional link between Toxoplasma gondii infection and congenital/early life and adult neurological clinical signs
Our data provide insight into the molecular mechanisms underpinning the association of HLA-DRB1 alleles with risk versus protection in visceral leishmaniasis in humans
We characterised the nasopharyngeal microbiome of these children in comparison to children with rAOM to identify potentially protective bacteria.
Rheumatic heart disease (RHD) after group A streptococcus (GAS) infections is heritable and prevalent in Indigenous populations. Molecular mimicry between human and GAS proteins triggers proinflammatory cardiac valve-reactive T cells.
Our results show perturbation of host mitochondrial function following T. gondii infection that likely impacts on pathogenesis of disease.
disease-deconvolution" identified associations between the parasite-brain interactions and epilepsy, movement disorders, Alzheimer's disease, and cancer.