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Gene editing and cardiac disease modelling for the interpretation of genetic variants of uncertain significance in congenital heart disease

Genomic sequencing in congenital heart disease (CHD) patients often discovers novel genetic variants, which are classified as variants of uncertain significance (VUS). Functional analysis of each VUS is required in specialised laboratories, to determine whether the VUS is disease causative or not, leading to lengthy diagnostic delays.

Activated Outside School Hours Care (OSHC)

Hayley Karen Christian Lombardi BSc (1st Class Hons), PhD (Distinction) W.Aust. BHSc (Hons), PhD Head, Child Physical Activity, Health and

BEACHES: Built Environments and Child Health in WalEs and AuStralia

The BEACHES project aims to provide high quality evidence of aspects of the built environment which can be modified to reduce the negative impact on children’s physical activity, eating behaviours and weight status.

Family Friendly Environments

Hayley Christian BSc (1st Class Hons), PhD (Distinction) W.Aust. Head, Child Physical Activity, Health and Development; Ascend Senior Research Fellow

The built environment and child obesity: A review of Australian policies

Child obesity is a serious public health challenge affected by both individual choice and societal and environmental factors. The main modifiable risk factors for child obesity are unhealthy eating and low levels of physical activity, both influenced by aspects of the built environment. 

Getting creative: Using art-based techniques to identify how arts organizations enhance young people’s well-being

Mental health concerns present significant challenges for Australian youth. Arts organizations play a key role in promoting preventative mental health strate-gies through enhancing the social and emotional well-being (SEWB) of youth. However, little is known about how the arts promote SEWB and the processes and contexts through which this occurs. 

Australian children's physical activity and screen time while in grandparental care

The objective of this study was to explore Australian children's engagement in physical activity and screen time while being cared for by their grandparents.

Organizational readiness and implementation fidelity of an early childhood education and care-specific physical activity policy intervention: findings from the Play Active trial

Many children do not accumulate sufficient physical activity for good health and development at early childhood education and care (ECEC). This study examined the association between ECEC organizational readiness and implementation fidelity of an ECEC-specific physical activity policy intervention.

Supporting nutrition education in low socioeconomic schools in Western Australia

School-based nutrition education (NE) has an important role in promoting healthy eating habits and helping prevent chronic diseases – particularly among disadvantaged children and youth who are more likely to experience poor diet quality.