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Frequently asked questions

Here are some of the most common questions about phage, phage therapy and antimicrobial resistance (AMR).

The Western Australian Paediatric Bronchiectasis Program

Bronchiectasis is a condition where the lungs become damaged and prone to infections.

Western Australian Epithelial Research Program

The Western Australian Epithelial Research Program (WAERP) is a community cohort biobank that collects and stores airway cells from the upper (nose) and lower (trachea) airways of Western Australian children and adults (1-50 years of age) undergoing non respiratory elective surgery.

Current Studies

The Western Australian Epithelial Research Program (WAERP) biobank is undertaking a number of research projects intended to improve the understanding and preclinical assessment of therapeutics for respiratory conditions.

Research Team

The Australian Epithelial Research Program (WAERP) comprises of several parties, including our Chief Investigators, Compliance, Scientific and Clinical Teams, and our Student group.

Scientific Advisory Committee

The Scientific Advisory Committee's (SAC) role is to provide scientific direction and to ensure the objectives of WAERP are reflected in the research performed; SAC forms part of our governance structure.

FAQs

Want to know how to be involved with WAERP? Or how long the project is running for? View our Frequently Asked Questions (FAQs) for answers to these questions and more.

Pseudomonas aeruginosa modulates neutrophil granule exocytosis in an in vitro model of airway infection

A population of neutrophils recruited into cystic fibrosis (CF) airways is associated with proteolytic lung damage, exhibiting high expression of primary granule exocytosis marker CD63 and reduced phagocytic receptor CD16. Causative factors for this population are unknown, limiting intervention. Here we present a laboratory model to characterize responses of differentiated airway epithelium and neutrophils following respiratory infection.

Association between early respiratory viral infections and structural lung disease in infants with cystic fibrosis

Infants with cystic fibrosis (CF) develop structural lung disease early in life, and viral infections are associated with progressive lung disease. We hypothesized that the presence of respiratory viruses would be associated with structural lung disease on computed tomography (CT) of the chest in infants with CF.