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Autism spectrum disorder (ASD) has a complex inheritance pattern and is more common in males. Etiologic models suggest that most ASD risk is transmitted through common and rare de novo genetic variation. It has been hypothesized that rare variation could be inherited and therefore contribute to the overall risk burden in subsequent generations, especially through female lineage in disorders with male-skewed sex ratios.
The aim of this study was to investigate the influence of children's autism characteristics, sensory profiles and feeding difficulties on caregiver-reported impact at mealtimes.
The Kids' autism research takes place at CliniKids, a centre that integrates world-class research with a clinical service for children with developmental delay and/or autism and their families.
Early motor impairments have been reported in children with neurodevelopmental disorders (NDD), but it is not clear if early detection of motor impairments can identify children at risk for NDD or how early such impairments might be detected. Our aim was to characterize early motor function in children later diagnosed with NDD relative to typically developing children or normative data.
There is insufficient evidence to draw conclusions on the efficacy of modified diets, hyperbaric oxygen therapy, immune therapy, and vitamin and fatty acid...
Data linkage is the bringing together of specific datasets from different sources using demographic information on individuals within a population.
Findings show that indicators of a poor intrauterine environment are associated with an elevated risk of ID, while for ASD, and particularly ASD without ID,...
Our findings provide additional insight into the early clinical profile of Rett syndrome.
Increased prenatal testosterone exposure has been hypothesized as a mechanism underlying autism spectrum disorders (ASD).
Professor Andrew Whitehouse has been awarded an Autism Spectrum Australia Recognition Award for his work communicating scientific findings to families.