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Research

Social impairments in autism spectrum disorder are related to maternal immune history profile

this study is the first to show an association between immune activation history in the mother and increased ASD symptom severity in children with ASD

Research

Does perinatal exposure to exogenous oxytocin influence child behavioural problems and autistic-like behaviours to 20 years of age

This study is the first to investigate longitudinal mental health outcomes associated with the use of oxytocin-based medications during labour

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Reduced heart rate variability in adults with autism spectrum disorder

Our data suggest an overall dysregulation in resting autonomic activity in adults with autism spectrum disorder

Research

The Comprehensive Autistic Trait Inventory (CATI): development and validation of a new measure of autistic traits in the general population

Traits and characteristics qualitatively similar to those seen in diagnosed autism spectrum disorder can be found to varying degrees in the general population. To measure these traits and facilitate their use in autism research, several questionnaires have been developed that provide broad measures of autistic traits [e.g. Autism-Spectrum Quotient (AQ), Broad Autism Phenotype Questionnaire (BAPQ)]. However, since their development, our understanding of autism has grown considerably, and it is arguable that existing measures do not provide an ideal representation of the trait dimensions currently associated with autism. Our aim was to create a new measure of autistic traits that reflects our current understanding of autism, the Comprehensive Autism Trait Inventory (CATI).

Research

Evidence for shared deficits in identifying emotions from faces and from voices in autism spectrum disorders and specific language impairment

While autism spectrum disorder (ASD) and specific language impairment (SLI) have traditionally been conceptualized as distinct disorders, recent findings...

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The relationship between maternal psychiatric disorder, autism spectrum disorder and intellectual disability in the child: a composite picture

Research conducted by this laboratory has previously published four papers examining the relationship between maternal psychiatric disorders and having a...

Research

Beyond the hype and hope: Critical considerations for intranasal oxytocin research in autism spectrum disorder

In this review, we comprehensively evaluate the rationale for oxytocin as a therapeutic, evaluating evidence from various various sources.

Research

Caesarean section and risk of autism across gestational age: a multi-national cohort study of 5 million births

The positive association between caesarean section (CS) and autism spectrum disorder (ASD) may be attributed to preterm delivery.

Research

Randomised controlled trial of an iPad based early intervention for autism: TOBY playpad study protocol

This trial will determine the effectiveness of the TOBY App as a therapeutic complement to other early interventions children with ASD receive

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Brief Report: Burden of Care in Mothers of Children with Autism Spectrum Disorder or Intellectual Disability

Mothers of children with autism spectrum disorder or intellectual disability have higher rates of treatment episodes for psychiatric disorders