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Research

The gut microbiome and cardiovascular disease: current knowledge and clinical potential

This review will focus on the role of the gut microbiome and associated functional components in the development and progression of atherosclerosis

Research

Host genetic factors in American cutaneous leishmaniasis: A critical appraisal of studies conducted in an endemic area of Brazil

This paper reviews American cutaneous leishmaniasis (ACL) immunogenetics in the state of Bahia (BA), northeastern Brazil, highlighting the interacting roles...

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Connective tissue growth factor is expressed in bone marrow stromal cells and promotes interleukin-7-dependent B lymphopoiesis

Hematopoiesis occurs in a complex bone marrow microenvironment in which bone marrow stromal cells provide critical support to the process through direct cell...

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Maternal and family factors and child eating pathology: Risk and protective relationships

This study aimed to identify maternal and family factors that may predict increases or decreases in child eating disorder symptoms over time, accounting for...

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Violence Risk Assessment in Australian Aboriginal Offender Populations: A Review of the Literature

The utilization of violence risk instruments in forensic populations is increasing and a plethora of empirical investigations support their ability to...

Research

A pre-clinical model of resistance to induction therapy in pediatric acute lymphoblastic leukemia

Relapse and acquired drug resistance in T-cell acute lymphoblastic leukemia (T-ALL) remains a significant clinical problem.

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Assessment and management of hypoglycemia in children and adolescents with diabetes

This paper provides clinical practice guidelines for treating low blood sugar in children and adolescents with Type 1 diabetes.

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Environmental, personal, and genetic determinants of response to vitamin D supplementation in older adults

We aimed to examine genetic and nongenetic determinants of change in serum 25-hydroxyvitamin D (25(OH)D) after supplementation.

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Human active X-specific DNA methylation events showing stability across time and tissues

The phenomenon of X chromosome inactivation in female mammals is well characterised and remains the archetypal example of dosage compensation via monoallelic...

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Keyhole limpet haemocyanin - A model antigen for human immunotoxicological studies

This report systematically reviews the human clinical studies that have used trans-cutaneous KLH immunization for assessment of the influence of various...