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Chinese immigrants living in Australia for a longer period of time have increased overall genome methylation and decreased overall gene expression
The introduction of class II tetramers for identifying antigen-binding CD41 cells has lagged behind the use of class I tetramers because of difficulties...
Early aberrant antibody responses, aeroallergen sensitised people, subclinical bacterial infection
Nutrition is one of the most easily modifiable environmental factors during early life that may play a role in allergic disease prevention.
Recent studies with synthetic peptides representing allergens and non-allergenic house dust mite proteins now offer new research avenues on HDM induced immune responses
There is a marked shift in innate and adaptive immune responses in Chinese immigrants after living in a Western environment for several years
Neonates have heightened susceptibility to infections. The biological mechanisms are incompletely understood but thought to be related to age-specific adaptations in immunity due to resource constraints during immune system development and growth. We present here an extended analysis of our proteomics study of peripheral blood-plasma from a study of healthy full-term newborns delivered vaginally, collected at the day of birth and on day of life (DOL) 1, 3, or 7, to cover the first week of life. The plasma proteome was characterized by LC-MS using our established 96-well plate format plasma proteomics platform.
Pneumococcal surface protein A is immunogenic and natural anti-PspA immune responses are acquired through exposure and develop with age
Honorary Emeritus Fellow; Scientific Reviewer - Animal Ethics
Benzathine penicillin G (BPG) is used as first-line treatment for most forms of syphilis and as secondary prophylaxis against rheumatic heart disease (RHD). Perceptions that poor quality of BPG is linked to reported adverse effects and therapeutic failure may impact syphilis and RHD control programs. Clinical networks and web-based advertising were used to obtain vials of BPG from a wide range of countries.