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Research

Genetic determinants of paediatric food allergy: A systematic review

We systematically reviewed the literature on the genetic basis of food allergy, identifying areas for further investigation

Research

Quorum Sensing Signaling Alters Virulence Potential and Population Dynamics in Complex Microbiome-Host Interactomes

Genome sequencing and phylogenetic analysis of a quorum sensing positive Psychrobacter isolate identified several quorum sensing associated systems

Research

An assessment of computer-generated stimuli for use in studies of body size estimation and bias

Our results show that perception of body size for computer-generated stimuli was non-linear

Research

Editorial: Insights Into Biomarkers, Cytokines, and Chemokines in Skin Cancer

Our current Research Topic highlights the complexity of the relationship between the skin, immune system and skin cancer

Research

Investing in school readiness: A comparison of different early childhood education pathways in rural Indonesia

This paper documents that children in rural Indonesia participate in a great variety of early childhood education pathways

Research

Narrowband UVB phototherapy reduces TNF production by B-cell subsets stimulated via TLR7 from individuals with early multiple sclerosis

At the end of a 60-day course of narrowband UVB phototherapy, administered to individuals with early multiple sclerosis, there were changes in the relative proportions of circulating B-cell subsets. This study investigated phototherapy-associated changes to cytokine responses of B cells when exposed to a TLR7 ligand.

Research

Planning and clinical role of acute medical home care services for COVID-19: consensus position statement by the Hospital-in-the-Home Society Australasia

During a pandemic when hospitals are stretched and patients need isolation, the role of hospital-in-the-home (HITH) providing acute medical care at home has never been more relevant. We aimed to define and address the challenges to acute home care services posed by the COVID-19 pandemic.

Research

Gain of chromosome 21 in hematological malignancies: lessons from studying leukemia in children with Down syndrome

Structural and numerical alterations of chromosome 21 are extremely common in hematological malignancies. While the functional impact of chimeric transcripts from fused chromosome 21 genes such as TEL-AML1, AML1-ETO, or FUS-ERG have been extensively studied, the role of gain of chromosome 21 remains largely unknown.

Research

Chronic health conditions, mental health and the school: A narrative review

School-based social risk processes in the lives of young people with chronic health conditions are likely to contribute to risk of psychological problems

Research

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

IL7 and glucocorticoids coordinately drive aberrant activation of PIM1 and suggests that T-ALL and T-LBL patients could benefit from PIM inhibition