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PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumoursOur findings define PTPN2 as a target for bolstering T-cell-mediated anti-tumour immunity and CAR T-cell therapy against solid tumours.
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Genome mining and characterisation of a novel transaminase with remote stereoselectivityHere we report a novel ω-transaminase discovered in a marine sponge Pseudovibrio sp. isolate
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Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironmentOur results identify a pretreatment tumor microenvironment that predicts response to immune checkpoint blockade, which can be therapeutically attained
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The Australian and New Zealand Children's Haematology/Oncology Group Biobanking NetworkThe ANZCHOG-BN is a new biobank network in Australasia that was developed to improve and streamline access to high-quality pediatric and AYA cancer biospecimens
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Impact of Micronutrient Status during Pregnancy on Early Nutrition ProgrammingGlobally and even in high-income countries where a balanced diet is generally accessible, an inadequate maternal micronutrient status is common
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The Nature and Quality of Australian Supermarkets' Policies that can Impact Public Health Nutrition, and Evidence of their Practical Application: A Cross-Sectional StudyFindings suggest Australian supermarket CSR policies are not likely to adequately contribute to improving population diets or sustainability of food systems
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Developmental vulnerabilities in children of chronically ill parents: A population-based linked data studyMaternal chronic illness is associated with an increased risk of poor developmental outcomes for children, particularly daughters
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Individualized prediction of transition to psychosis in 1,676 individuals at clinical high risk: Development and validation of a multivariable prediction modelThe aim of the study was to develop and validate an individualized, clinically based prognostic model for forecasting transition to psychosis from a CHR-P stage
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Geo-visual integration of health outcomes and risk factors using excess risk and conditioned choropleth mapsGhana remains a malaria hyperendemic region with district-level spatial heterogeneity
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Online Video Instruction on Hand Expression of Colostrum in Pregnancy is an Effective Educational ToolFindings suggest that the use of an online expert video is an acceptable and effective way to educate pregnant women in antenatal colostrum expression