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Research

Helicobacter pylori overcomes natural immunity in repeated infections

Helicobacter pylori infection does not promote an immune response protective against future reinfection

Research

Increased Body Mass Index during Therapy for Childhood Acute Lymphoblastic Leukemia: A Significant and Underestimated Complication

We undertook a retrospective review of children diagnosed with acute lymphoblastic leukemia (ALL) and treated with modern COG protocols to determine...

Research

Childhood Hospitalisation with Infection and Cardiovascular Disease in Early-Mid Adulthood: A Longitudinal Population-Based Study

We investigated whether childhood infection-related hospitalisation (IRH, a marker of severity) was associated with subsequent adult CVD hospitalisation.

Research

Two methods for engaging with the community in setting priorities for child health research: Who engages?

The Western Australian Telethon Kids Institute Participation Program employs a range of methods for fostering active involvement of community members in its...

Research

Cardiac autonomic dysfunction is associated with high-risk albumin-to-creatinine ratio in young adolescents with type 1 diabetes in AdDIT

This study examined the association between cardiac autonomic dysfunction and high albumin-to-creatinine ratio (ACR) in adolescents with type 1 diabetes.

Research

UV Irradiation of Skin Regulates a Murine Model of Multiple Sclerosis.

The prevalence of multiple sclerosis follows a latitude gradient, with increased disease at higher latitudes.

Research

The aggregation of early-onset melanoma in young Western Australian families

Results indicated a strong familial basis of melanoma, with the higher than expected hazard ratio observed likely to reflect early-age at onset cases in this...

Research

Novel CT domain-encoding splice forms of CTGF/CCN2 are expressed in B-lineage acute lymphoblastic leukaemia

Connective tissue growth factor (CTGF/CCN2) has been shown previously to be aberrantly expressed in a high proportion of paediatric precursor B cell acute...

Research

Clinical cardiovascular risk during young adulthood in offspring of hypertensive pregnancies:

Offspring of hypertensive pregnancies have increased cardiovascular risk factors during childhood.

Research

Immunogenicity and safety of single-dose, 13-valent pneumococcal conjugate vaccine in pediatric and adolescent oncology patients

All children who are receiving therapy for cancer should receive a single dose of PCV13 as soon as possible after diagnosis, regardless of prior PCV exposure.