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Associations between aggressive behaviour scores and cardiovascular risk factors in childhood

The objective of this study was to examine the influence of aggressive behaviour scores on cardiovascular disease (CVD) risk factors throughout childhood.

Early morbidity and mortality following in utero exposure to selective serotonin reuptake inhibitors

The early years of life have a profound effect on a child's developmental pathway.

Evaluation of a new measure of mood intolerance, the Tolerance of Mood States Scale (TOMS)

This research aimed to (i) validate a new measure of mood intolerance, the Tolerance of Mood States (TOMS) scale, and (ii) to examine associations between...

Intellectual disability and other neuropsychiatric outcomes in high-risk children of mothers with schizophrenia, bipolar disorder and unipolar major depression

We examined risk of intellectual disability and other neuropsychiatric outcomes in children of mothers with and without schizophrenia, bipolar or depression.

Premature to conclude no genetic basis to the association between smoking and major depressive disorder

We analyzed two large-scale surveys, and found high rates of smoking in people with mood disorders and both with and without substance dependence disorders.

Intersex adolescents seeking help for their depression: the case study of SPARX in New Zealand

SPARX is a computerized cognitive behavioral therapy self-help program for adolescent depression that is freely available in New Zealand. At registration, users identify themselves as either male, female, intersex, or transgender. We aimed to describe the mental health of adolescent intersex users. A secondary analysis of SPARX usage data over 5 years.

Associations of maternal and paternal mental health problems with offspring anxiety at age 20 years: Findings from a population-based prospective cohort study

Epidemiological studies indicate that children of parents with mental health problems are at an increased risk of developing anxiety disorders. Few studies have investigated this relationship in young adults. Participants were from the Raine Study, which is a multi-generational birth cohort study in Australia. Maternal anxiety and depression in late childhood were assessed using the Depression, Anxiety, and Stress Scale (DASS-42), and paternal lifetime mental health problems were assessed using a self-reported questionnaire.

Maternal and paternal mental health problems and the risk of offspring depression in late adolescence: findings from the Raine study

There are limited studies on the risk of depressive symptoms in adolescent offspring exposed to parental mental health problems in middle childhood. We investigated the association between parental mental health problems, particularly paternal emotional problems and maternal symptoms of anxiety and depression, and the risk of depressive symptoms in adolescent offspring aged 17.

Maternal prenatal stress exposure and sex-specific risk of severe infection in offspring

Maternal stressful life events during pregnancy have been associated with immune dysregulation and increased risk for asthma and atopy in offspring. Few studies have investigated whether prenatal stress is associated with increased overall or specific infectious diseases in childhood, nor explored sex differences. We sought to examine the relationship between the nature and timing of maternal stress in pregnancy and hospitalisation with infection in offspring.

Best practice when working with suicidal behaviour and self-harm in primary care: a qualitative exploration of young people's perspectives

General practitioners (GPs) have a key role in supporting young people who present with suicidal behaviour/self-harm. However, little is known about young people's opinions and experiences related to GPs' practices for such presentations, and their decisions to disclose suicidal behaviour/self-harm to GPs. Additionally, existing guidelines for the management of suicide risk and/or self-harm have not incorporated young people's perspectives. This study aimed to explore young people's views and experiences related to the identification, assessment and care of suicidal behaviour and self-harm in primary care settings with GPs.