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Andrew Shattock PhD, MSc, BSc (Hons) Honorary Team Member andrew.shattock@thekids.org.au Dr Andrew Shattock is an Honorary Team Member of The Kids

The first few days of life are characterized by rapid external and internal changes that require substantial immune system adaptations. Despite growing evidence of the impact of this period on lifelong immune health, this period remains largely uncharted. 

Streptococcus pneumoniae is a leading cause of pneumonia and meningitis worldwide. Many different serotypes co-circulate endemically in any one location. The extent and mechanisms of spread and vaccine-driven changes in fitness and antimicrobial resistance remain largely unquantified.

A The Kids Research Institute Australia researcher will work to better understand the immune system mechanisms that cause multiple sclerosis, thanks to a new grant from MS Australia. 

Disease spreading models such as the ubiquitous SIS compartmental model and its numerous variants are widely used to understand and predict the behavior of a given epidemic or information diffusion process. A common approach to imbue more realism to the spreading process is to constrain simulations to a network structure, where connected nodes update their disease state based on pairwise interactions along the edges of their local neighborhood. 

Influenza vaccine effectiveness and immunogenicity can be compromised with repeated vaccination. We assessed immunological markers in a cohort of healthcare workers (HCW) from six public hospitals around Australia during 2020-2021.

Eight The Kids Research Institute Australia researchers are among those who have received grant funding from the Telethon-Perth Children’s Hospital Research Fund (TPCHRF).

Three outstanding young researchers from The Kids Research Institute Australia have been named Raine Fellows and received valuable Raine Priming Grants to support their child health research.