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To look at the interplay between PMN and macrophages in disease progression in humans we asked whether polymorphisms at genes that regulate their infiltration..

Senior Research Fellow

A researcher's work from 20 years ago has helped to crack one of biology’s biggest mysteries.

Once upon a time it was infectious diseases like polio, measles or tuberculosis that most worried parents. With these threats now largely under control, parents face a new challenge – sky-rocketing rates of non-infectious diseases such as asthma, allergies and autism.

GWAS results provide firm confirmation for the importance of antigen presentation and the regulation of IFNγ in determining the outcome of Leishmania infections

Our data set provides a useful reference point for genomic studies on Aboriginal Australians

There is insufficient evidence available to determine whether these organisms are pathogens, commensals or contribute indirectly to the pathogenesis of OM

Amphotericin B provides improved therapy for visceral leishmaniasis (VL) caused by Leishmania donovani

We confirmed the strong association between high DAT and/or rK39 titers and progression to disease among asymptomatic subjects

To understand how HLA-DR contributes to disease pathogenesis, we examined expression at the protein level in circulating myeloid and lymphoid cells of VL patients