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Research
Distinct Streptococcus pneumoniae cause invasive disease in Papua New GuineaStreptococcus pneumoniae is a key contributor to childhood morbidity and mortality in Papua New Guinea (PNG). For the first time, whole genome sequencing of 174 isolates has enabled detailed characterisation of diverse S. pneumoniae causing invasive disease in young children in PNG, 1989-2014.
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Changes in thymic regulatory T-cell maturation from birth to puberty: Differences in atopic childrenWe report vaccine efficacy against CIN3+ and adenocarcinoma in situ (AIS) in the end-of-study analysis of PATRICIA (PApilloma TRIal against Cancer In young...
Research
Dahlem ConferenceThere is increasing evidence that the functional state of the immune system at birth is predictive of the kinetics of immune maturation in early infancy.
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A retrospective population-based cohort study identifying target areas for prevention of acute lower respiratory infections in childrenAcute lower respiratory infections (ALRI) are a major cause of hospitalisation in young children
Research
The anti-inflammatory effects of interleukin-4 are not mediated by suppressor of cytokine signalling-1 (SOCS1)While it is known that the anti-inflammatory effects of interleukin (IL)-4 require new protein synthesis, the exact mechanisms by which IL-4 suppresses the prod
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IgG Responses to Pneumococcal and Haemophilus Influenzae Protein Antigens Are Not Impaired in Children with a History of Recurrent Acute Otitis MediaVaccines including conserved antigens from Streptococcus pneumoniae & nontypeable Haemophilus influenzae have the potential to reduce of otitis media.
News & Events
National honour for infectious diseases researcherPerth researcher dedicated to reducing serious chest and ear infections in children has been recognised with the award of Officer in the Order of Australia
News & Events
Trial begins of first vaccine against Ross River VirusPerth researchers are seeking volunteers to test the effectiveness of a vaccine against the debilitating Ross River Virus.
News & Events
New vaccine promises fewer needlesPerth researchers are calling for help from Perth toddlers and their parents to participate in a new project that aims to reduce the number of injections
Research
Impact of Meningococcal ACWY Vaccination Program during 2017-18 Epidemic, Western Australia, AustraliaThe rising incidence of invasive meningococcal disease (IMD) caused by Neisseria meningitidis serogroup W in Western Australia, Australia, presents challenges for prevention. We assessed the effects of a quadrivalent meningococcal vaccination program using 2012-2020 IMD notification data.