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Research

Pediatric Brain Tumors: Innovative Genomic Information Is Transforming the Diagnostic and Clinical Landscape.

This article summarizes data from collaborative group and institutional trials that have advanced the science of pediatric brain tumors.

Research

Cross-presentation of cutaneous melanoma antigen by migratory XCR1+CD103− and XCR1+CD103+ dendritic cells

This report provides new insight into the functional specialization within the broad network of dendritic cells that are responsible for skin immunosurveillance

Research

Disruptive mood dysregulation disorder in ICD-11: a new disorder or ODD with a specifier for chronic irritability

This letter congratulates Mulraney et al. regarding their paper on disruptive mood dysregulation disorder in children with ADHD.

Research

Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood.

This study identifies widespread DNA methylation changes in whole blood associated with childhood obesity.

Research

Supply of benzathine penicillin G: the 20-year experience in Australia

Reliable supplies of BPG are essential for delivering the recommended schedule of secondary prophylaxis for people living with RHD.

Research

Response to Comment on Lin et al. Risk Factors for Decline in IQ in Youth With Type 1 Diabetes Over the 12 Years From Diagnosis/Illness Onset

This editorial response addresses each of the concerns raised by Lin et al. RE: Risk Factors for Decline in IQ in Youth With Type 1 Diabetes Over the 12...

Research

Breastfeeding and nutrition to 2 years of age and risk of childhood acute lymphoblastic leukemia and brain tumors

Acute lymphoblastic leukemia and childhood brain tumors are 2 of the most common forms of childhood cancer, but little is known of their etiology.

Research

The relationship between ambient ultraviolet radiation (UVR) and objectively measured personal UVR exposure dose is modified by season and latitude

Season and latitude modify the relationship between ambient ultraviolet radiation and personal ultraviolet radiation exposure

Research

T cells recognizing a 11mer influenza peptide complexed to H-2D b show promiscuity for peptide length

T-cell repertoire is selected according to self peptide-MHC (major histocompatibility complex) complexes in the thymus.

Research

ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure.

Two important risk factors for this disease are a positive family history and elevated intraocular pressure (IOP), which is also highly heritable.