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Biological changes associated with T-ALL relapse and resistance are stochastic and highly individual

Identified CCI-007 as a novel small molecule that displays rapid toxicity towards a subset of MLL-r, CALM-AF10 and SET-NUP214 leukemia cell lines

In this investigation, the authors found an association between home pesticide exposure before birth and during a child's early years and acute lymphoblastic...

This paper demonstrated that home paint exposure shortly before conception, during pregnancy, and/or after birth appeared to increase the risk of childhood ALL.

This report provides new insight into the functional specialization within the broad network of dendritic cells that are responsible for skin immunosurveillance

This article summarizes data from collaborative group and institutional trials that have advanced the science of pediatric brain tumors.

We undertook a retrospective review of children diagnosed with acute lymphoblastic leukemia (ALL) and treated with modern COG protocols to determine...

This article investigates the impact of burn & excisional injury on the immune system.

Haematological malignancies, although a broad range of specific disease types, continue to show considerable overlap in classification, and patients are...

Connective tissue growth factor (CTGF/CCN2) has been shown previously to be aberrantly expressed in a high proportion of paediatric precursor B cell acute...