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Research

Suicide prevention in LGBTQA+ young people: Best practice guidelines for clinical and community service providers

These guidelines outline a set of best practices for suicide prevention in LGBTQA+ young people, targeting both clinical and community service providers.

Research

Systems biology of mitochondrial diseases

Investigators: Professor Aleksandra Filipovska, Dr Stefan Siira Project description  This project will focus on new and cutting-edge development of

Research

The Adult Migrant English Program (AMEP) Impact Evaluation Project

This project evaluates the effectiveness of the Adult Migrant English Program (AMEP). To date, we have produced five research reports submitted to the Australian Government Department of Home Affairs.

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The Cardiovascular Risk Evaluation in Expectant Fathers (CARE-Dads) Study

Susan Prescott MBBS BMedSci PhD FRACP Honorary Research Fellow susan.prescott@thekids.org.au Honorary Research Fellow Susan Prescott is a Professor

Research

Short-course oral co-trimoxazole versus intramuscular benzathine benzylpenicillin for impetigo in a highly endemic region

The major burden of disease is in developing and tropical settings where topical antibiotics are impractical and lead to rapid emergence of antimicrobial...

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'I can sit and talk to her': Aboriginal people, chronic low back pain and healthcare practitioner communication

Chronic low back pain (CLBP) is a complex issue to manage in primary care and under-researched in Aboriginal populations.

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Basophil counts in PBMC populations during childhood acute wheeze/asthma are associated with future exacerbations

Our findings suggest that the proportion of degranulated basophils can also be associated with recurrent exacerbations

Research

Functional differences in airway dendritic cells determine susceptibility to IgE-sensitization

Respiratory IgE-sensitization to innocuous antigens increases the risk for developing diseases such as allergic asthma.

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Immunological processes driving IgE sensitisation and disease development in males and females

In this review, we discuss recent mechanistic studies casting further light on how the expression of sex hormones may influence the innate and adaptive immune system

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Role of stem cell precursors in tissues

We have recently published a paper identifying precursor populations in peripheral lung (2017), and have also discovered that these populations can be found in multiple tissues.

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Mapping changes in immune cell populations in gestational tissues over the course of pregnancy

This is a strategic “pilot” project in which we are seeking basic information on the immune cell content of gestational tissues.

Research

Boosting airway T-regulatory cells by gastrointestinal stimulation as a strategy for asthma control

The hallmark of atopic asthma is transient airways hyperresponsiveness (AHR) preceded by aeroallergen-induced Th-cell activation.

Pregnancy and Early Life Immunology

The Pregnancy and Early Life Immunology team's overall research vision is targeted towards understanding immunological development during early life.

Research

Epigenetic changes underpinning allergen sensitization: a twin-based study

We are studying immune cells from identical twins of which one suffers and one does not suffer from allergic disease to identify specific mechanisms that may play important roles in disease development.