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Research

Relationship between the neighbourhood built environment and early child development

The relationship between features of the neighbourhood built environment and early child development was investigated

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Undiagnosed Diseases Network International (UDNI): White paper for global actions to meet patient needs

This white paper discusses the global progress in understanding novel diseases with the aim of encouraging more collaboration between international...

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The effectiveness of influenza vaccination in preventing hospitalisation in children in Western Australia

This study aimed to determine the vaccine effectiveness of the southern hemisphere trivalent inactivated influenza vaccine (TIV) in preventing...

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Influenza-Associated Encephalitis/Encephalopathy Identified by the Australian Childhood Encephalitis Study 2013-2015

We aimed to describe case of Influenza associated encephalitis/encephalopathy identified by the Australian Childhood Encephalitis study

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DeepCAGE Transcriptomics Reveal an Important Role of the Transcription Factor MAFB in the Lymphatic Endothelium

VEGFR-3 signaling plays a central role in lymphatic biology, both in the development of the lymphatic network during embryogenesis as well as in...

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Understanding the aetiology and resolution of chronic otitis media from animal and human studies

This Clinical Puzzle article describes our current knowledge of chronic otitis media and the existing research models for this condition

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Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood.

This study identifies widespread DNA methylation changes in whole blood associated with childhood obesity.

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Current options in aerosolised drug therapy for children receiving respiratory support

In this review, we explore current knowledge and provide guidance as to when and how the inhaled route may be of value when treating patients whose tracheas are intubated

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The potential of phage therapy in cystic fibrosis

This review summarises the phage-microbe-human lung interactions in CF that must be addressed to successfully develop and deliver phage to CF airways

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Children and young people at risk of disengagement from school

The review examines the international literature to determine how disengagement can be defined & understood, & then examines student disengagement in Australia.

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Patterns of Alcohol Intake of Pregnant and Lactating Women in Rural Western Australia

This paper will present the first alcohol consumption data of pregnant and breastfeeding women living in rural Western Australia

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Linked data research: a valuable tool in the ART field

This letter to the editor endorses data linkage studies and cites their potential value over other types of epidemiological studies within the field of...

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Barriers to Addressing Social Determinants of Health in Pediatric Nursing Practice: An Integrative Review

The greatest barrier to addressing the social determinants of health in the pediatric context is the dominance of the 'medical model' of care

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The relationship between school climate and mental and emotional wellbeing over the transition from primary to secondary school

The current study examined the relationship between students’ mental and emotional wellbeing and factors pertaining to school climate, focusing on the...

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Immunogenicity and safety of single-dose, 13-valent pneumococcal conjugate vaccine in pediatric and adolescent oncology patients

All children who are receiving therapy for cancer should receive a single dose of PCV13 as soon as possible after diagnosis, regardless of prior PCV exposure.

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Disruptive mood dysregulation disorder in ICD-11: a new disorder or ODD with a specifier for chronic irritability

This letter congratulates Mulraney et al. regarding their paper on disruptive mood dysregulation disorder in children with ADHD.

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Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC

Epigenetically regulated genes have a great theranostic potential, especially in tumors with no apparent driver mutations.

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How many infants are temperamentally difficult?

In this letter, the authors respond to the commentary on Chong et al. “How many infants are temperamentally difficult?”; by correcting errors, & then...

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Phase 2 of CATALISE: a multinational and multidisciplinary Delphi consensus study of problems with language development: Terminology

Lack of agreement about criteria and terminology for children's language problems affects access to services as well as hindering research and practice.

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Streptococcus pneumoniae and Haemophilus influenzae in paediatric meningitis patients at Goroka General Hospital

This research presents serotype, antimicrobial susceptibility and outcome data from paediatric meningitis patients prior to introduction of Haemophilus...