The Strep A Burden of Disease Working Group (BoDWG) was first established in 2020 through the Strep A Global Vaccine Consortium (SAVAC). This group comprises 19 members from 7 geographically diverse countries representing 5 WHO regions with expertise in clinical medicine, epidemiology, surveillance, health economics and global vaccine policies covering Strep A and other vaccine-preventable diseases. The group had a commitment to advise SAVAC on the key burden of disease issues that need resolving to progress the prevention of Strep A through vaccination. With limited funding, the group has made important contributions to the success of SAVAC. This included the publication of a series of standardized Strep A surveillance protocols which established the framework methodology for surveillance activities within SAVAC 2.0, development and publication of a seminal “data purpose matrix” to guide prioritization of data for Strep A vaccine development, and development of a list of priority research projects focused on burden of disease.
The purpose of the BoDWG is to build the evidence base around the Strep A burden of disease, with a particular focus on data that may accelerate development and implementation of Strep A vaccines. This will be done by establishing a community of practice around Strep A burden of disease and epidemiology global research as well as continuing to provide strategic advice to SAVAC 2.0, in particular Workstream 1: Preparing for vaccine trial sites. The BoDWG will also engage in new research activities as decided by the group. The Secretariat of the BoDWG and its organisation will reside within The Kids Research Institute Australia.