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Research

Ca-EDTA restores the activity of ceftazidime-avibactam or aztreonam against carbapenemase-producing Klebsiella pneumoniae infections

Developing an effective therapy to overcome carbapenemase-positive Klebsiella pneumoniae (CPKp) is an important therapeutic challenge that must be addressed urgently. Here, we explored a Ca-EDTA combination with aztreonam or ceftazidime-avibactam in vitro and in vivo against diverse CPKp clinical isolates.

Research

A Research Translation, Implementation and Impact Strategy for the Australian Healthy Environments and Lives (HEAL) Research Network

Healthy Environments And Lives (HEAL) is the Australian national research network established to support improvements to health, the Australian health system, and the environment in response to the unfolding climate crisis. The HEAL Network comprises researchers, community members and organisations, policymakers, practitioners, service providers, and other stakeholders from diverse backgrounds and sectors.

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Overcoming the challenges of caring for a child with foetal alcohol spectrum disorder: a Pilbara community perspective

The caregivers in this study have gained valuable knowledge and wisdom through caring for a child with FASD

Research

Upper Airway Pathology Contributes to Respiratory Symptoms in Children Born Very Preterm

The upper airway may play a role in the respiratory symptoms experienced by some very preterm children and should be considered by clinicians

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Effect of Fluoxetine on Obsessive-Compulsive Behaviors in Children and Adolescents With Autism Spectrum Disorders: A Randomized Clinical Trial

Treatment with fluoxetine compared with placebo resulted in significantly lower scores for obsessive-compulsive behaviors at 16 weeks

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Soy Biodiesel Exhaust is More Toxic than Mineral Diesel Exhaust in Primary Human Airway Epithelial Cells

Exposure to biodiesel exhaust resulted in significantly greater cell death and a greater release of immune mediators compared to both air controls and ULSD exhaust

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S. aureus colonization in healthy Australian adults receiving an investigational S. aureus 3-antigen vaccine

Based on descriptive analyses of this small study, S. aureus 3-antigen vaccine vaccination did not impact S. aureus acquisition or carriage

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A cross-sectional examination of the clinical significance of autistic traits in individuals experiencing a first episode of psychosis

Results suggest that autism traits are associated with poorer clinical presentation in first-episode psychosis populations

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Modelling the effects of beverage substitution during adolescence on later obesity outcomes in early adulthood: Results from the raine study

Sugar-sweetened beverage intake during adolescence was associated with higher body mass index, waist circumference, and being overweight in early adulthood