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Research

novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

This study thus identified a novel small molecule that rapidly kills MLL-rearranged leukemia cells by targeting a metabolic vulnerability

Research

Differential SLC6A4 methylation: a predictive epigenetic marker of adiposity from birth to adulthood

These data suggest that altered methylation of CpG loci within SLC6A4 may provide a robust marker of adiposity across the life course

Research

Gender-affirming hormones and surgery in transgender children and adolescents

This Review explores the available published evidence on gender-affirming cross-sex hormone and surgical interventions in transgender children

Research

Still keen and committed: piloting an instrument for identifying positive veteran teachers

Initial findings suggest the potential of the instrument in helping identifying positive veteran teachers within systems, as well as the voracity of the research approach

Research

An economic case for a vaccine to prevent group A streptococcus skin infections

A vaccine that prevents GAS cellulitis and other skin infections, in addition to throat infections, would maximise its value and commercial viability

Research

Primary prevention of rheumatic fever in the 21st century: evaluation of a national programme

Population-based primary prevention of ARF through sore throat management may be effective in well-resourced settings like New Zealand

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Hesitant compliers': Qualitative analysis of concerned fully-vaccinating parents

Parents interpreted pivotal vaccine-related events in the community as requiring them to take personal responsibility for vaccine decisions

Research

Global supermarkets' corporate social responsibility commitments to public health: A content analysis

Investigate the world's largest and most powerful supermarkets' publically available CSR commitments to determine their potential impact on public health

Research

A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis

Here we report that CHAF1B is required for normal hematopoiesis while its overexpression promotes leukemia