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Glioma-specific Domain IV EGFR cysteine mutations promote ligand-induced covalent receptor dimerization and display enhanced sensitivityEpidermal growth factor receptor (EGFR) is over-expressed in many brain tumors. This paper examines mutations the EGFR that make the cell it is produced in...
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The evolution of clinical trials for infant acute lymphoblastic leukemiaDespite initial improvements in survival of infants with ALL since establishment of the first pediatric cooperative group ALL trials, the poor outcome has...
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Assisted reproductive technology and birth defects: A systematic review and meta-analysisIt has been 10 years since we carried out a systematic search of the literature on birth defect risk in infants born following assisted reproductive...
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Evaluating hypoxia during air travel in healthy infantsUp to a third of ex-preterm infants flying near term exhibit pulse oxygen saturation (SpO2) of less than 85% during air travel.
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Survey of clinical infant lung function testing practicesTo evaluate current ILF testing practices and to survey users regarding the indications, limitations and perceived clinical benefits of ILF testing.
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Involving consumers and the community in the development of a diagnostic instrument for fetal alcohol spectrum disorders in AustraliaAustralia's commitment to consumer and community participation in health and medical research has grown over the past decade.
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Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitizationAllergen-specific immunoglobulin E (present in allergic sensitization) has a central role in the pathogenesis of allergic disease.
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Early life arsenic exposure and acute and long-term responses to influenza A infection in miceExposure to arsenic in early life has been shown to increase the rate of respiratory infections during infancy, reduce childhood lung function, and increase...
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Resident CD8+ and Migratory CD103+ Dendritic Cells Control CD8 T Cell Immunity during Acute Influenza InfectionThe identification of the specific DC subsets providing a critical role in presenting influenza antigens to naïve T cell precursors remains contentious and...
Research
Improved long-term survival in patients on combination therapies following an incident acute myocardial infarction: A longitudinal population-based studyTo investigate the single and combined effectiveness of commonly prescribed secondary preventive medications (post-acute myocardial infarction (AMI)) in...