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Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweightWe find that DNA methylation in neonatal blood is associated with birthweight, with a difference in birthweight ranging from -183 to 178 grams per 10% increase in methylation
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Dendritic cells and cancer: From biology to therapeutic interventionIn this review, we discuss the different subsets of tumor-infiltrating dendritic cells and their role in anti-tumor immunity
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Statistical Analysis Plan for "An international study of isoelectric electroencephalography events in infants and young children during anesthesia for surgery"This Statistical Analysis Plan details the statistical procedures to be applied for the analysis of data for the multicenter electroencephalography study
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Tobacco smoking and mental disorders in Australian adolescentsThis study aimed to (1) examine the strength of the association between mental disorders/mental health problems, risk behaviours and tobacco smoking among Australian adolescents, (2) compare rates of tobacco smoking among Australian adolescents with major depressive disorder, attention-deficit/hyperactivity disorder and/or conduct disorder in 2013/14 vs 1998, and (3) identify the extent to which an association between tobacco smoking and mental health problems among adolescents can be attributed to non-mental health risk factors.
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Chronic health conditions, mental health and the school: A narrative reviewSchool-based social risk processes in the lives of young people with chronic health conditions are likely to contribute to risk of psychological problems
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Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphomaIL7 and glucocorticoids coordinately drive aberrant activation of PIM1 and suggests that T-ALL and T-LBL patients could benefit from PIM inhibition
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Germline Elongator mutations in Sonic Hedgehog medulloblastomaGenetic predisposition to proteome instability may be a determinant in the pathogenesis of paediatric brain cancers
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The development of a consensus statement for the prescription of powered wheelchair standing devices in Duchenne muscular dystrophyPURPOSE: To develop a consensus statement for the prescription of a Powered Wheelchair Standing Device (PWSD) in young people with Duchenne muscular dystrophy (DMD). MATERIALS AND METHODS: An international multidisciplinary panel comprising clinicians and users (young people with DMD) along with their parents was consulted. A literature review was undertaken and a Delphi method was utilised to generate consensus statements.
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Rheumatic heart disease in pregnancy: Profile of women admitted to a Western Australian tertiary obstetric hospitalThis retrospective study assessed maternal and perinatal outcomes for women with rheumatic heart disease admitted to the largest tertiary obstetric hospital
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Vitamin D receptor polymorphisms are associated with severity of wheezing illnesses and asthma exacerbations in childrenThese findings suggest that genetic variants at the VDR locus may play a role in acute wheeze/asthma severity in children