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Research

Differential Sensitivity of Human Hepatocellular Carcinoma Xenografts to an IGF-II Neutralizing Antibody May Involve Activated STAT3

These findings implicate the activation of STAT3 as one pathway that may mediate resistance to IGF-II-targeted therapy in HCC

Research

The Canmore Declaration: Statement of Principles for Planetary Health

We provide the Canmore Declaration, a Statement of Principles for Planetary Health

Research

Does otitis media in early childhood affect later behavioural development? Results from the Western Australian Pregnancy Cohort (Raine) Study

The relationship between early life episodes of otitis media and later behavioural development with adjustment for confounders.

Research

Respiratory function in healthy Emirati children using forced oscillations

Forced oscillation technique measurements were feasible in Emirati school-children. New forced oscillation technique reference equation in Emirati children were derived.

Research

Teleaudiology services for rehabilitation with hearing aids in adults: A systematic review

This review provides up-to-date evidence for teleaudiology hearing aid services in new and experienced hearing aid users in different practice settings

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Partial trisomy 21 contributes to T-cell malignancies induced by JAK3-activating mutations in murine models

This JAK3A572V knockin model is a relevant new tool for testing the efficacy of JAK inhibitors in JAK3-related hematopoietic malignancies

Research

Cellular and molecular mechanisms of vitamin D in food allergy

Epidemiological evidence from the past decade suggests a role of vitamin D in food allergy pathogenesis

Research

Cochrane corner: hearing aids for mild to moderate hearing loss in adults

The evidence supports the widespread provision of hearing aids as the first-line clinical management for those seeking help for hearing difficulties

Research

Using linked data to investigate developmental vulnerabilities in children of convicted parents

Although children of convicted parents experience a higher incidence of sociodemographic risk, their parents' criminal activity constitutes an independent risk factor for their development

Research

Large-Scale Structural Variation Detection in Subterranean Clover Subtypes Using Optical Mapping

The accuracy of structural variations detection by Bionano optical mapping is highly dependent on the quality of reference genomes and the density of selected nickases