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Beyond Seizures as an Outcome Measure: A Global Severity Scoring System for CDKL5 Deficiency DisorderCDKL5 deficiency disorder (CDD) is a rare developmental and epileptic encephalopathy (DEE) associated with multiple impairments and comorbidities. Outcome measures for disease-modifying clinical trials for DEEs should measurably capture a spectrum of caregiver priorities and be externally validated.
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Convalescent plasma in hospitalised patients with COVID-19Convalscent plasma (CP) was identified as a potential therapy for COVID-19 available early in the pandemic.
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Global risk of selection and spread of Plasmodium falciparum histidine-rich protein 2 and 3 gene deletionsSince their first detection in 2010, Plasmodium falciparum malaria parasites lacking the P. falciparum histidine-rich protein 2 gene (pfhrp2) have been observed in 40 of 47 surveyed countries, as documented by the World Health Organization. These genetic deletions reduce detection by the most widely used rapid diagnostic tests, prompting three countries to switch to alternative diagnostics.
Research
A meta-analytic review and conceptual model of the antecedents and outcomes of goal adjustment in response to striving difficultiesThere is growing interest in how and why individuals adjust their goals in response to difficulties encountered during goal striving and the outcomes of such adjustments; however, research on these topics is fragmented across theoretical perspectives and life domains.
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Key appointments to drive early childhood collaborationLeading child health researcher Professor Donna Cross has been appointed as Director of the new Early Childhood Development and Learning Collaboration, hosted b
Discover the impact of our achievements in the "real world".
A small group program to help parents tackle anxiety in young children diagnosed with autism has found significant improvements in both children’s anxiety and parental mental health and wellbeing.
When author Maurice Sendak first sketched out the story of a rambunctious little boy sent to his room without supper, there’s no way he could have known his rollercoaster tale of childhood imagination would still be speaking to the hearts of wild young things more than six decades on.
More than 80,000 Australian children are expected to benefit from a trial being rolled out to 700 childcare centres across the country that aims to boost declining physical activity levels.
What if researchers could shop for different data to help uncover how, when and why chronic conditions such as asthma, obesity, allergies and poor mental health develop?