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Primary central nervous system lymphoma: Initial features, outcome, and late effects in 75 children and adolescentsChildren with Primary Central Nervous System Lymphoma and no immunodeficiency have a good outcome
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Cochrane corner: interventions to prevent hearing loss caused by noise at workThe aim of this Cochrane Review was to find out if hearing loss caused by noise at work is being prevented by current interventions
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Topical antiseptics for chronic suppurative otitis mediaThe effectiveness and safety profile of antiseptics in the treatment of chronic suppurative otitis media is uncertain
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Early life exposure to coal mine fire smoke emissions and altered lung function in young childrenInfant exposure to coal mine fire emissions could be associated with long-term impairment of lung reactance
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Pediatric Burn Survivors Have Long-Term Immune Dysfunction With Diminished Vaccine ResponseEpidemiological studies have demonstrated that survivors of acute burn trauma are at long-term increased risk of developing a range of morbidities. The mechanisms underlying this increased risk remain unknown. This study aimed to determine whether burn injury leads to sustained immune dysfunction that may underpin long-term morbidity. Plasma and peripheral blood mononuclear cells were collected from 36 pediatric burn survivors >3 years after a non-severe burn injury (<10% total body surface area) and from age/sex-matched non-injured controls.
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RSV prophylaxis use in high-risk infants in Western Australia, 2002-2013: a record linkage cohort studyThe monoclonal antibody, palivizumab is licensed for use in high-risk infants to prevent severe illness caused by respiratory syncytial virus (RSV). The level of its use and compliance with current jurisdictional guidelines which were amended in 2010, is unknown.
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Clinical protocol for a longitudinal cohort study to identify markers of vaccine immunogenicity in newborn infants in the gambia and papua New GuineaImmunity is distinct in early life and greater precision is required in our understanding of mechanisms of early life protection to inform development of new pediatric vaccines
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Lessons from schools with high levels of support for students with type 1 diabetes: A qualitative studyThis project aimed to investigate how schools provide support for the psychosocial wellbeing and disease management of students with type 1 diabetes
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Genetics, Transcriptomics and Meta-Taxonomics in Visceral LeishmaniasisVisceral leishmaniasis (VL) caused by parasites of the Leishmania donovani complex can be fatal in susceptible individuals. Understanding the interactions between host and pathogen is one way to obtain leads to develop better drugs and for vaccine development. In recent years multiple omics-based approaches have assisted researchers to gain a more global picture of this interaction in leishmaniasis. Here we review results from studies using three omics-based approaches to study VL caused by L. donovani in India.
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Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome?Baseline signatures might contribute to identifying interventional targets to be modulated prior to vaccination in order to improve vaccination responses